Metformin affects intracellular metabolism and has a different mechanism of action than losartan (image) Kumamoto University Share Print E-Mail Caption Metformin, unlike losartan, also targets amelioration of metabolic abnormalities. Credit Professor Hirofumi Kai Usage Restrictions Adapted from Fig. 5(b, c, d) of Omachi, K. et.al., Scientific Reports, 2021. This image is made available under the terms of CC by 4.0. Any further distribution of this work must follow the terms of this license. Share Print E-Mail Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.