CD36 trajectories in a primary human macrophage from a
10 Hz/10 s single-molecule movie. Scale bar, 2 μm. Red, linear
trajectories; cyan, isotropic trajectories. The linear motion of
receptors, which depends on the actin meshwork and on microtubules,
enhances receptor clustering in the absence of ligand, priming the
macrophages to respond when exposed to ligand.