This image, from the same case, shows highly abnormal fluorescent signals from cancer cell telomeres (red) that are indicative of the ALT telomere maintenance phenotype. All cell nuclei here are stained blue with the fluorescent dye, DAPI. This image relates to an article that appeared in the June 30, 2011, issue of Science Express, published by AAAS. The study, by C.M. Heaphy of Johns Hopkins Medical Institutions in Baltimore, Md., and colleagues was titled, "Altered Telomeres in Tumors with ATRX and DAXX Mutations."