Allosteric Machines (image) Scripps Research Institute Share Print E-Mail Caption More than 50 percent of therapeutic drugs target GPCRs, including allergy and heart medication, drugs that target the central nervous system, and anti-depressants. Based on scientists' emerging understanding of GPCRs, this image represents GPCRs as complex machines, controlled not only by their pharmacological ligands, but also by sodium, cholesterol, lipids, and water. Credit Image by Yekaterina Kadyshevskaya, GPCR Network, The Scripps Research Institute Usage Restrictions None Share Print E-Mail Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.