New Studies Sharpen the Precision of Genome Editing (2 of 2) (image) American Association for the Advancement of Science Share Print E-Mail Caption An artist's rendition of genome engineering using enzymes from the microbial CRISPR/Cas immune system. The Cas9 nuclease can be recruited to distinct locations on the genome by RNA "guides" to introduce breaks in the genome and facilitate editing of the DNA sequence. The CRISPR-based genome engineering technology is efficient and simple to use and may find broad applications in both research and medicine. This image relates to a paper that appeared in Jan. 3, 2013, issue of Science Express, published by AAAS. The paper, by Le Cong at Broad Institute of MIT and Harvard in Cambridge, Mass., and colleagues was titled, "Multiplex Genome Engineering Using CRISPR/Cas Systems." Credit Image courtesy of Stephen Dixon and Feng Zhang Usage Restrictions Please cite the owner of the image when publishing. This image may be freely used by reporters as part of news coverage, with proper attribution. Non-reporters must contact Science for permission. Share Print E-Mail Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.