Disease-Causing Proteins in Brain Disorders (image) University of Pennsylvania School of Medicine Share Print E-Mail Caption This shows the wing posture in a normal fly and a fly with hnRNPA2 mutation. The mutant fly is weak and unable to maintain normal wing posture. Muscle histology shows that hnRNPA2 is nuclear in normal flies, but accumulates in innumerable cytoplasmic aggregates in flies with the hnRNPA2 mutation. Credit Nam Chul Kim, St. Jude Children's Research Hospital; Nature Usage Restrictions None Share Print E-Mail Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.