These are digital images showing what the arteriole-venule shunts in a tiny biopsy of human palmar skin look like as seen under the microscope. The processing of the biopsy caused the sensory nerve fibers to appear yellow and the sympathetic nerve fibers to appear green. A shunt in a woman without fibromyalgia is shown to the left and a shunt from a woman with fibromyalgia is shown to the right. The woman with fibromyalgia has an excessive quantity of nerve fibers around her shunt. The increase mostly occurs among the sensory nerve fibers.
Frank L. Rice, PhD,
Integrated Tissue Dynamics, LLC