Amplification of c-MET: A Study of Resistance to Anti-EGFR Therapies in Colorectal Cancer (video) European Society for Medical Oncology Share Print E-Mail Loading video... Caption F. Ciardiello shares his comments on a next generation sequencing study applied to identify genetic alterations in patients with metastatic colorectal cancer who do not develop K-ras mutations during the course of therapy with cetuximab and panitumumab. The analysis revealed a high level of amplification of the MET proto-oncogene. The emergence of MET amplification in circulating, cell-free, DNA may be used to select patients most likely to benefit from anti-MET therapies. http://www.esmo.org Credit © European Society for Medical Oncology Usage Restrictions None Share Print E-Mail Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.