Study Shows Where Alzheimer's Starts and How it Spreads (image) Columbia University Medical Center Share Print E-Mail Caption Alzheimer's disease starts in the entorhinal cortex (yellow). Using fMRI in mouse (left) and human (right) brains, the researchers provide evidence that the disease spreads from the entohrinal cortex (yellow) to other cortical regions (red) -- the perirhinal cortex and posterior parietal cortex. Credit Usman Khan/lab of Scott A. Small, MD, Columbia University Medical Center. Usage Restrictions Only grant use of images in the context of this research story Share Print E-Mail Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.