Nanoparticle Aggregation in Biological Systems (image) World Scientific Share Print E-Mail Caption Nanoparticle aggregation in biological systems can occur due to interactions with ions (phosphate buffered saline, PBS), proteins (fetal bovine serum, FBS), extracellular matrix, and cells. Aggregation of iron oxide nanoparticles leads to significant reductions in heating potential and MR imaging contrast, but here we also demonstrate an empirical correlation between the two, providing new ability for image guidance of iron oxide nanoparticle heating in the clinic. Credit Authors Usage Restrictions None Share Print E-Mail Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.