For each of the risk categories, Stitziel and his colleagues calculated the number of patients that doctors would need to treat with statins to prevent one heart attack over a 10-year period. This 'number needed to treat' statistic also showed the greater benefit of statins in patients in the high genetic-risk category. As an example, using data from the JUPITER clinical trial (Justification for the Use of Statins in Primary Prevention: an Intervention Trial Evaluating Rosuvastatin), they stratified participants into groups at low, intermediate and high risk of having a heart attack. In the high-risk group, researchers calculated 25 people would need to take a statin for 10 years to prevent one heart attack. Such a strategy could help doctors decide which patients are at high risk and therefore most likely to benefit from statin therapy.