Cocaine Use Causes 'Profound Changes' in the Brain (video) University of East Anglia Share Print E-Mail Loading video... Caption Cocaine use causes 'profound changes' in the brain that lead to an increased risk of relapse due to stress -- according to new research from the University of East Anglia. New research published today in The Journal of Neuroscience identifies a molecular mechanism in the reward centre of the brain that influences how recovering cocaine addicts might relapse after stressful events. Credit University of East Anglia Usage Restrictions None Share Print E-Mail Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.