MRI Detects Early Breast Cancer Metastases in Mice (image) NIH/National Institute of Biomedical Imaging & Bioengineering Share Print E-Mail Caption Metastasis occurs when cells are shed from primary breast cancer tumor and establish a new tumor at a distant site. For early detection of the metastasis with MRI, the Lu Lab at Case Western University developed a probe that binds to fibrin-fibronectin protein complexes in high-risk tumors. Fibronectin is expressed in high-risk (aggressive) cancer and not in normal tissue, so MRI imaging is able to distinguish metastases from normal tissue. Credit Lu Lab, CWRU. Usage Restrictions None Share Print E-Mail Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.