What The Study Did: This randomized clinical trial of patients with severe COVID-19 was stopped early after results from another trial were released but this study investigated whether intravenous hydrocortisone (administered either as a seven-day fixed-dose course or restricted to when shock is clinically evident) improved 21-day organ support-free days.
Authors: Derek C. Angus, M.D., M.P.H., of the University of Pittsburgh, is the corresponding author.
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###Media advisory: The full study and editorial are linked to this news release. This study is being published to coincide with the release of guidelines from the World Health Organization regarding use of corticosteroids for treatment of critically ill COVID-19 patients.
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