New full-term placental stem cells could transform research on late-pregnancy complications
Peer-Reviewed Publication
Updates every hour. Last Updated: 2-Sep-2025 23:11 ET (3-Sep-2025 03:11 GMT/UTC)
Pregnancy complications such as preeclampsia and preterm birth often arise during the late stage of pregnancy. However, researchers have primarily relied on placental cells from early pregnancy to study these conditions, which may not fully reflect the biology of late-stage complications. Now, a research team in Japan has successfully developed human placental stem cells from the smooth chorion (a part of the placenta) taken from full-term pregnancies. These new stem cells, called Ch-TS cells, share the same characteristics as placental stem cells from early pregnancy and can develop into the key cell types essential for proper placental function. This advancement allows scientists to study placental complications using cells from the actual time period when these complications occur, potentially leading to better understanding, earlier detection, and improved treatments for pregnancy-related conditions.
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