Through a few clever molecular hacks, researchers at Columbia University Medical Center have converted a natural bacterial immune system into a microscopic data recorder, laying the groundwork for a new class of technologies that use bacterial cells for everything from disease diagnosis to environmental monitoring.
The most dramatic divergence between humans and other primates can be found in the brain, the primary organ that gives our species its identity. However, all regions of the human brain have molecular signatures very similar to those of our primate relatives, yet some regions contain distinctly human patterns of gene activity that mark the brain's evolution and may contribute to our cognitive abilities, a new Yale-led study has found.
Researchers at Sanford Burnham Prebys Medical Discovery Institute (SBP) have identified a signaling pathway that is essential for angiogenesis, the growth of new blood vessels from pre-existing vessels. The findings, published in Nature Communications, may improve current strategies to improve blood flow in ischemic tissue, such as that found in atherosclerosis and peripheral vascular disease associated with diabetes.
A new study that included researchers from Norway, the University of Washington, the University of California San Diego and The University of Texas Health Science Center at San Antonio (now called UT Health San Antonio™) found that dozens of small molecules called metabolites are altered in this disease.
Cigars may have a reputation for being safer than cigarettes, but they may be just as harmful and addictive, according to Penn State researchers, who add that small cigars have just as much if not more nicotine than cigarettes.
A team of researchers at Whitehead has illuminated an important role for different subtypes of muscle cells in orchestrating the process of tissue regeneration. Notably, in the absence of these muscles, regeneration fails to proceed.
A team of neuroscientists at the University of Pennsylvania has constructed the first whole-brain map of electrical connectivity in the brain based on data from nearly 300 neurosurgical patients with electrodes implanted directly on the brain. The researchers found that low-frequency rhythms of brain activity, when brain waves move up and down slowly, primarily drive communication between the frontal, temporal and medial temporal lobes, key brain regions that engage during memory processing.
Glucocorticoids, a class of steroid hormone medications often prescribed to patients with Duchenne muscular dystrophy, offer long-term benefits for this disease, including longer preservation of muscle strength and function and decreased risk of death.
A study of more than 400 adults with prehypertension, or stage 1 high blood pressure, found that combining a low-salt diet with the heart-healthy DASH diet substantially lowers systolic blood pressure -- the top number in a blood pressure test -- especially in people with higher baseline systolic readings.
Blocking the action of a key protein frees oxygen to damage iron-dependent proteins in lung and breast cancer cells, making them easier to kill.