Past studies have shown that biparental care of offspring can be affected negatively when females and males are exposed to bisphenol A (BPA. In a study published today in the journal PLOS One, researchers at the University of Missouri found that mice pups whose grandparents had been exposed to BPA, had different vocalization patterns. This, in turn, could also affect the amount of parental care they received. Scientists believe results could have important relevance to humans.
In 2013 and 2015, devastating outbreaks of ZIKA captured world attention. The virus is often transmitted from wild animals -- probably non-human primates -- via mosquitos to humans. This is the first comprehensive study to investigate which mammal species may host the ZIKA virus (ZIKV). 'We systematically tested the ability of ZIKV to infect cells from humans, great apes, New World and Old World monkeys, and mice,' explained Princeton Professor Alexander Ploss.
Glial cells surround neurons and provide support -- not unlike hospital staff and nurses supporting doctors to keep operations running smoothly. These often-overlooked cells, which include oligodendrocytes and astrocytes, are the most abundant cell types in the central nervous system. But these cells do more than support neurons. They also actively influence them, University of California, Riverside, researchers report.
An ASU research team focused on measuring the stiffness, bending, twisting and viscosity of individual cells -- focused on a breast cancer cell line -- using all of the most state-of-the art technology at their disposal. How both healthy and cancerous cells respond to this environment -- and whether there are key differences that can be identified for future diagnostic applications was of keen interest to both the NCI and the physicists taking on the NCI's challenge.
Scientists have captured the most information yet about proteins within a single human cell, giving scientists one of their clearest looks yet at the molecular happenings inside a human cell. The team detected on average more than 650 proteins in each cell -- many times more than conventional techniques capture from single cells.
AcuraStem, a fast-growing and innovative biotech company located in Monrovia, California, has been awarded a 3.7 million dollar Small Business Innovation Research (SBIR) Fast-Track grant (#R44NS105156) by the National Institute of Neurological Disorders and Stroke (NINDS) to continue research for the development of a small molecule therapeutic, 'AS2015', focused on treating patients with the genetic form of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) caused by expansion repeats in the gene C9ORF72.
New data published in Nature Biotech, represents the largest ever analysis of immune cell signaling research, mapping more than 3,000 previously unlisted cellular interactions, and yielding the first ever immune-centric modular classification of diseases. These data serve to rewrite the reference book on immune-focused inter-cellular communications and disease relationships. New Data Published by Nature Biotechnology: Covering 16,000,000 scientific articles, this massive Natural Language Processing (NLP) project quadruples the reference body of organized inter-cellular signalling interactions, plots inter-cellular immune profiles for 188 diseases and creates the first ever immune-centered map of disease similarities and differences.
Carnegie Mellon neuroscientists have mapped the feeling of cool touch to the brain's insula in a mouse model. The findings provide an experimental model that will advance research into conditions like pain and hypersensitivity to cold and help researchers to continue to unravel the multifaceted ways touch is represented in the brain.
Researchers at VCU Massey Cancer Center in Richmond, Virginia, have identified a promising target to reverse the development of high-risk neuroblastoma and potentially inform the creation of novel combination therapies for the disease.
The study of a Quebec family with an unusual gene provides novel insight into how our brain is built and, according to the McGill-led team of scientists, offers a better understanding of psychiatric disorders such as depression, addictions and schizophrenia.