Using a simple 'mirror trick' and not-so-simple computational analysis, scientists affiliated with the Marine Biological Laboratory (MBL) have considerably improved the speed, efficiency, and resolution of a light-sheet microscope, with broad applications for enhanced imaging of live cells and embryos.
In a new longitudinal observational study, scientists at Beth Israel Deaconess Medical Center (BIDMC) looked at the relationships among maternal snoring, childhood snoring and children's metabolic characteristics -- including body mass index (BMI) and insulin resistance, which reflects future risk for developing diabetes and cardiovascular disease -- in approximately 1,100 children followed from gestation through early adolescence.
Alzheimer's disease (AD) is known to cause memory loss and cognitive decline, but other functions of the brain can remain intact. The reasons cells in some brain regions degenerate while others are protected is largely unknown. In a paper to be published in Stem Cell Reports, researchers from Brigham and Women's Hospital have found that factors encoded in the DNA of brain cells contribute to the patterns of degeneration, or vulnerability, in AD.
Specially tailored, ultrafast pulses of light can trigger neurons to fire and could one day help patients with light-sensitive circadian or mood problems, according to a new study in mice at the University of Illinois. This study is the first demonstration of using coherent control to regulate function in a living cell.
A new study published today -- World Prematurity Day -- in the American Journal of Obstetrics & Gynecology provides additional support for treatment with vaginal progesterone to reduce the risk of preterm birth, neonatal complications and infant death in pregnant women with a short cervix. A shortened cervix is the most powerful predictor of preterm birth.
Boosting activity in brain areas related to thinking and problem-solving may also protect against worsening anxiety, suggests a new study by Duke University scientists. Using noninvasive brain imaging, the researchers found that at-risk people were less likely to develop anxiety if they had higher activity in a region of the brain responsible for complex mental operations. The results may be a step towards tailoring psychological therapies to the specific brain functioning of individual patients.
Researchers from Boston Medical Center, in conjunction with researchers from Florida State University and others across the country, are collaborating on a study that aims to get parents involved with early intervention services sooner.
Prematurity is the main complication of pregnancy, and 15 million babies are born preterm worldwide each year. Physicians worldwide have investigated whether vaginal progesterone administration to women with a mid-trimester sonographic short cervix reduces the rate of preterm birth. Now physicians and researchers have found that when all available information is considered in an individual patient data meta-analysis, the results are clear: vaginal progesterone reduces the rate of preterm birth at <28, <30, <32, <34, <35, and <36 weeks.
A Northwestern University research team is the first to capture on video organic nanoparticles colliding and fusing together. This unprecedented view of 'chemistry in motion' will aid Northwestern nanoscientists developing new drug delivery methods as well as demonstrate to researchers around the globe how an emerging imaging technique opens a new window on a very tiny world.
The immune cells that are trained to fight off the body's invaders can become defective. It's what allows cancer to develop. So most research has targeted these co-called effector T-cells. But a new study takes a step back and considers: What if the problem isn't with the effector T-cells but starts higher up the cellular chain?