People who carry a genetic susceptibility to Alzheimer's disease appear to be at greater risk of diminished cognition from sleep-disordered breathing than those without the susceptibility, according to new research published online, ahead of print in the Annals of the American Thoracic Society.
A cooperative research team led by researchers at Dartmouth's Norris Cotton Cancer Center devised a strategy to target cancer cells while sparing normal cells by capitalizing on vulnerabilities that are exposed only in tumor cells. These vulnerabilities are known as the 'Achilles heel' of cancer cells. Although much is known about the mutations that cause a cell to become malignant, little is known about these vulnerabilities. The team has published new findings on this topic.
Northwestern University neuroscientists now can visualize how fruit flies sense and process humidity and temperature together through a 'sensory map' within their brains, according to new research. The findings could one day help researchers better understand how the human brain simultaneously processes humidity and temperature and might influence how humans control for mosquitoes in cities and prevent mosquito-borne diseases.
As outlined in a study published today in Nature, lead author Devin Sok, Director, Antibody Discovery and Development at the International AIDS Vaccine Initiative (IAVI), reports the elicitation of powerful, HIV-blocking antibodies in cows in a matter of weeks -- a process that usually takes years in humans. The unexpected animal model is providing clues for important questions at a moment when new energy has infused HIV vaccine research.
New research provides insight into how changes that occur with age may predispose breast tissue cells to becoming cancerous. Specifically, the study demonstrates that regions in the genome where DNA methylation changes occur with age are particularly sensitive to disruption in cancer. This new data provides insight into how certain molecular changes with age in normal breast tissue itself may contribute to breast cancer risk.
Irregular heartbeat -- or arrhythmia -- can have sudden and often fatal consequences. A biomedical engineering team at Washington University in St. Louis examining molecular behavior in cardiac tissue recently made a surprising discovery that could someday impact treatment of the life-threatening condition.
Whether a melanoma patient will better respond to a single immunotherapy drug or two in combination depends on the abundance of certain white blood cells within their tumors, according to a new study conducted by UC San Francisco researchers joined by physicians from UCSF Health.
University of South Florida biologists have found that a crucial window in the development of tadpoles may influence a frog's later ability to fight infectious diseases as an adult.
Several studies have reported associations between proton-pump inhibitor (PPI) use and dementia. New research published this week in Gastroenterology, the official journal of the American Gastroenterological Association (AGA), puts these claims to rest. The study authors report that there is no convincing evidence to support the suggestion that PPI use increases dementia risk.
Biologists at the University of Connecticut and University of South Florida have found that a crucial window in the development of tadpoles may influence a frog's ability to fight infectious diseases as an adult. The scientists showed that an early-life disruption of the gut and skin bacterial communities of tadpoles later affects the adult frogs' ability to fight off parasitic gut worms.