'What has been missing in clinical trials may just be the timing of the treatments,' says first author Lynsey Fettig.
NRG-RTOG 0436 has determined that adding an epidermal growth factor receptor (EGFR) inhibitor to a chemo-radiation regimen does not improve overall survival for patients with locally advanced esophageal cancer treated in a non-operative manner. These results are reported in 'Effect of the Addition of Cetuximab to Paclitaxel, Cisplatin, and Radiation Therapy for Patients with Esophageal Cancer -- The NRG Oncology RTOG 0436 Phase 3 Randomized Clinical Trial,' which was recently published in the Journal of the American Medical Association Oncology.
African-Americans typically have worse outcomes from smoking-related cancers than Caucasians, but the reasons for this remain elusive. However, scientists at Wake Forest Baptist Medical Center have taken a big step toward solving this puzzle.
A toddler running sometimes loses footing because both feet come off the ground at the same time. Kinesin motors that move materials around in cells have the same problem, which limits how fast they can traverse a microtubule in the cell and carry cargo, according to Penn State researchers who have now seen these kinesin motors move using an unusual microscope and tagging method.
Images of the brain's gray and white matter obtained with multiple MRI techniques can help identify and track cognitive impairment in active professional fighters, according to a new study.
Educational videos delivered by text or email successfully encouraged new mothers to use safe sleep practices for their babies, reducing the risk of sudden unexpected infant death, a new study has found.
Transgender people who are married are less likely to experience discrimination than their unmarried counterparts, indicates a national study led by a Michigan State University sociologist.
Scientists from the Memorial Sloan Kettering Cancer Center, US, have revealed a communication system between the knee joint and developing bones in mice, which controls bone growth during early development and after injury.
A new study has shown that infusion of a broadly neutralizing antibody VRC01 in virally suppressed, early treated volunteers was associated with a modestly delayed rebound of HIV after interruption of antiretroviral therapy.
A lack of variation in the stress hormone cortisol from morning to evening is tied to a wide range of negative health conditions, including inflammation and immune system dysfunction, new Northwestern University research suggests. In the first comprehensive review of the relationship between daily cortisol fluctuations and health, researchers at the School of Education and Social Policy combined data from 80 different studies to show that while cortisol levels matter, a lack of variation from morning to evening may be even more telling.