Among US adults who were established smokers in the past five years, those who use e-cigarettes daily were significantly more likely to have quit cigarettes compared to those who have never tried e-cigarettes. Over half of daily e-cigarette users had quit smoking in the past five years, compared to 28 percent who had never tried e-cigarettes. This is one of the first studies to reveal the patterns of cessation prevalence among e-cigarette users.
Chemists have discovered a powerful pain reliever that acts on a previously unknown pain pathway. The compound is as effective at relieving neuropathic pain in injured mice as a drug widely used for pain relief called gabapentin. If they can demonstrate that it is safe, effective and nonaddictive in humans -- a process that typically takes years -- the discovery could address one of today's biggest public health challenges: the opioid abuse epidemic.
A virus that infects a species of malaria-transmitting mosquito could help scientists gain a better understanding of mosquito biology and eventually could lead to methods for stopping or slowing the spread of the disease, according to a researcher in Penn State's College of Agricultural Sciences.
Scientists have used magnetism to activate tiny groups of cells in the brain, inducing bodily movements that include running, rotating and losing control of the extremities -- an achievement that could lead to advances in studying and treating neurological disease.
Using fragments of circulating tumor DNA in blood, University of California San Diego School of Medicine researchers were able to identify theoretically targetable genetic alterations in 66 percent of patients with cancer of unknown primary (CUP), a rare disease with seven to 12 cases per 100,000 people each year.
A five-year federal research grant totaling $1,887,049 to Jackson Laboratory research scientist Yanjiao Zhou, M.D., Ph.D., will fund studies exploring the therapeutic potential of the gut microbiome in multiple sclerosis.
Researchers at Case Western Reserve University School of Medicine have developed a method that could make magnetic resonance imaging -- MRI -- multicolor. Current MRI techniques rely on a single contrast agent injected into a patient's veins to vivify images. The new method uses two at once, which could allow doctors to map multiple characteristics of a patient's internal organs in a single MRI. The strategy could serve as a research tool and even aid disease diagnosis.
New information about how and where the innate immune system fights off viral infections that enter through the skin could lead to better treatments for viruses like Zika, dengue and measles, according to Penn State College of Medicine researchers. The innate immune system is the body's first line of defense, providing broad protection as opposed to the specific immune system which targets the specific threat.
An experimental drug combined with the traditional chemotherapy drug cisplatin, when used in mice, destroyed a rare form of salivary gland tumor and prevented a recurrence within 300 days, a University of Michigan study found.
Identifying the basic cellular malfunction underlying amyotrophic lateral sclerosis and a form of dementia opens the pathway to developing treatments to prevent the disease by preserving neurons.