Researchers found a relationship between the genetics of tumors with germline BRCA1/2 mutations and whether the tumor retains the normal copy of the BRCA1/2 gene, and risk for primary resistance to a common chemotherapy that works by destroying cancer cells' DNA.
A new in vitro study by University of California, Davis, researchers indicates that quaternary ammonium compounds, or 'quats,' used as antimicrobial agents in common household products inhibit mitochondria, the powerhouses of the cell, as well as estrogenic functions in cells. Quats are used as antiseptics in toothpastes, mouthwashes, lozenges, nasal sprays, eye drops, shampoos, lotions, intravaginal spermicidal sponges and household cleaners, to name a few.
A new longitudinal study suggests that the types of peer relationships youth make in high school matter for mental health through young adulthood.
A new study sought to identify factors that predict infants' avoidance and resistance, looking specifically at how mothers respond physiologically and emotionally to their infants' distress.
New research led by University of Pennsylvania biologists and published this week in the journal Nature Genetics has identified small sequences in plant DNA that act as signposts for shutting off gene activity, directing the placement of proteins that silence gene expression.
Scientists have pinpointed how a tiny protein seems to make the deadly Ebola virus particularly contagious.
University at Buffalo researchers have assembled a team of three antibiotics that, together, are capable of eradicating E. coli carrying mcr-1 and ndm-5 -- genes that make the bacterium immune to last-resort antibiotics.
Researchers have revealed the existence of a new quorum-sensing molecule that increases the virulence of the pathogenic bacterium Pseudomonas aeruginosa.
Breast cancer cells with defects in the DNA damage repair-genes BRCA1 and BRCA2 have a mutational signature known in cancer genomics as 'Signature 3.' But not all breast tumor cells exhibiting Signature 3 have BRCA1 or BRCA2 mutations. Therefore, some consider Signature 3 a biomarker for 'BRCAness,' a sign of a breakdown in BRCA-related DNA repair in general and not BRCA damage in particular.
Texas Biomedical Research Institute Associate Scientist Dr. Marie-Claire Gauduin has partnered with Dr. Chinnaswamy Jagannath, professor at McGovern Medical School at UTHealth in Houston to test a modified TB vaccine that, if effective, could prove more powerful and provide longer lasting immunity. Dr. Gauduin and Dr. Jagannath are principal investigators on this five-year, $4.4 million study funded by the National Institutes of Health.