A new study by researchers at Wake Forest Baptist Medical Center has shown that aggressive lowering of blood pressure in people with hypertension reduced the risk of left ventricular hypertrophy (LVH). This condition, the enlargement and thickening of the walls of the heart's main pumping chamber, is the most common complication of high blood pressure and greatly increases the risk of developing cardiovascular disease.
Researchers from Princeton University's Department of Molecular Biology have identified a small RNA molecule that helps maintain the activity of stem cells in both healthy and cancerous breast tissue. The study, which will be published in the June issue of Nature Cell Biology, suggests that this 'microRNA' promotes particularly deadly forms of breast cancer and that inhibiting the effects of this molecule could improve the efficacy of existing breast cancer therapies.
Genes responsible for hypoplastic left heart syndrome identified using mouse models.
Tests of cells collected from the umbilical cord blood vessel walls at birth can predict death or poor pulmonary outcomes in extremely preterm infants, say researchers at the University of Alabama at Birmingham.
In a recent paper published online in the journal Critical Care Medicine, researchers at the Johns Hopkins Armstrong Institute of Patient Safety and Quality led a study that demonstrated that health care providers can take steps to curb ventilator-associated events.
Caltech biochemists have uncovered details of a protein that controls blood cell production in an aggressive form of leukemia.
A national study of college and university administrators has found that female department chairs, deans and provosts have different attitudes and beliefs than their male counterparts about how to retain women professors in STEM fields. It also supports the assertion that placing women in administrative roles creates greater emphasis on the importance of enacting policies to attract and retain women in STEM.
Directly injecting a tumor with an agent that activates a natural, powerful tumor suppressor enhances the drug's capacity to attack the tumor both locally and where it spreads, scientists report in the journal Cancer Research.
Much of what we thought we knew about the human papilloma virus (HPV) in HPV-related head and neck cancers may be wrong, according to a newly published study by Virginia Commonwealth University (VCU) researchers that analyzed data from The Human Cancer Genome Atlas. Head and neck cancers involving HPV are on the rise, and many experts believe we are seeing the start of an epidemic that will only get worse in the coming years.
Research indicates that in mice with a KRAS mutation, present in 90 percent of pancreatic cancer patients, expressing only half the amount of the glucose-regulated protein GRP78 is enough to halt the earliest stage of pancreatic cancer development, resulting in delayed tumor development and prolonged survival.