For the first time, scientists have shown that a female fruit fly's pheromone signals can actually tell males how much energy her body has invested in egg production versus in storing away energy for her own survival. And it's a signal that she can't change in order to make herself more attractive.
Cedars-Sinai neuroscience investigators have found that Alzheimer's disease affects the retina -- the back of the eye -- similarly to the way it affects the brain. The study also revealed that an investigational, noninvasive eye scan could detect the key signs of Alzheimer's disease years before patients experience symptoms.
Adding another reason for doctors to avoid the overuse of antibiotics, new research shows that a reduction in the variety of microbes in the gut interferes with the immune system's ability to fight off disease.
A drug-like molecule developed by Duke Health researchers appears to intercede in an inflammatory response that is at the center of a variety of diseases, including some cancers, rheumatoid arthritis and Crohn's disease.
Immortalization of cells is a necessary step in the development of cancer, and scientists think that the main cause is turning on an enzyme -- telomerase -- that lengthens chromosomal telomeres and prevents normal cell death. A new study by UC Berkeley scientists shows that turning on telomerase is not a one-step process. In melanoma, and probably other cancers, a mutation turns up telomerase slightly, keeping the cell alive long enough for other changes that up-regulate telomerase.
A new study suggests it may be possible to slow dangerous infections by manipulating the messages microbes send to one another, allowing the body to defeat an infection without causing the bacteria to develop resistance to the treatment.
The study found that female college-aged students who reported at least one period of daily self-weighing over a two-year study saw a drop in their body mass index.
Rosalind Franklin University of Medicine and Science researcher Joanna Dabrowska has been awarded a five-year, $2 million grant from the National Institutes of Health to investigate the role of the hormone oxytocin in stress-induced psychiatric disorders. Her findings could lead to urgently needed new drug therapies for generalized anxiety and post-traumatic stress disorders.
In this issue of JCI Insight, researchers at Cedars-Sinai Medical Center adapted a noninvasive retinal imaging approach to characterize amyloid-β deposition, the pathological hallmark of Alzheimer's disease, in the retinas of patients and healthy controls. This imaging enabled detection and quantification of amyloid-β, revealing increased deposits in Alzheimer's patients compared to controls. These results demonstrate the feasibility of this approach as a tool for earlier Alzheimer's diagnosis and intervention.
New findings challenge existing dogma that neurons release fixed amounts of chemical signal at any one time and could have implications for brain disorders including Parkinson's and schizhophrenia.