More than a quarter of children with autism spectrum disorder are also diagnosed with disruptive behavior disorders. For the first time, Yale researchers have identified a possible biological cause: a key mechanism that regulates emotion functions differently in the brains of the children who exhibit disruptive behavior.
A new material automatically 'listens' to the brain, leading to more sensitive electronics that could detect neurological disease sooner.
For immigrants to the United States, the current political climate, and debates over issues such as a border wall, become part of the environment that influences their health, according to a new University of Washington study.
A study lead by Penn Medicine researchers found that childhood trauma is linked to abnormal connectivity in the brain in adults with major depressive disorder (MDD). The paper, published this week in Proceedings of the National Academy of Sciences (PNAS), is the first data-driven study to show symptom-specific, system-level changes in brain network connectivity in MDD.
A new study assessing data from 620,000 individuals found that the 18 most highly-studied candidate genes for depression are no more associated with depression than randomly chosen genes.
New research in rodents reveals for the first time how dopamine changes the function of the brain's prefrontal cortex. In a study published today in the journal Cell Reports, researchers found that dopamine has little effect on individual cells. Instead, it generates sustained activity in the ensemble of cells in the prefrontal cortex that lasts for up to 20 minutes.
Damage to parts of the orbitofrontal cortex (OFC), a region within the prefrontal cortex, heightens monkeys' defensive responses to threat, according to new research published in JNeurosci. The study proposes a critical role for subregions of this brain area in different anxiety disorders.
A single allergic reaction during pregnancy prompts sexual-development changes in the brains of offspring that last a lifetime, new research suggests. Female rats born to mothers exposed to an allergen during pregnancy acted more characteristically 'male' -- mounting other female rodents, for instance -- and had brains and nervous systems that looked more like those seen in typical male animals.
Using strong and targeted but noninvasive magnets at specific sites in the brains of people with and without mild learning and memory problems, Johns Hopkins researchers report they were able to detect differences in the concentrations of brain chemicals that transmit messages between neurons. The strength of these magnetic fields allows the researchers to measure tiny amounts and compare multiple brain metabolite levels at the same time. These studies may ultimately help to reveal what initiates memory decline and may, perhaps, even predict dementia risk.
Researchers at the Medical University of South Carolina have identified which neurons are responsible for cocaine-seeking behaviors in rodents and where these neurons exert their effects within the brain. Their findings were published in March 13, 2019 issue of The Journal of Neuroscience. This work opens a new line of addiction research that could lead to novel therapeutic approaches for preventing relapse.