The research, published in Current Biology, is one of the first comprehensive characterizations of poorly formed memories and may offer a framework to explore different therapeutic approaches to fear, memory and anxiety disorders. It may also have implications for accuracy of some witness testimony.
MIT scientists have identified a potential new strategy for treating Fragile X syndrome, a disorder that is the leading heritable cause of intellectual disability and autism. In a study of mice, the researchers showed that inhibiting an enzyme called GSK3 alpha reversed many of the behavioral and cellular features of Fragile X.
Traumatic stress can cause aggression by strengthening two brain pathways involved in emotion, according to research recently published in JNeurosci. Targeting those pathways via deep brain stimulation may stymie aggression associated with post-traumatic stress disorder.
Study offers molecular explanation for long-standing observation that certain diseases occur more often or more severely in different sexes. Complement component 4 (C4) genes protect against the autoimmune disorders lupus and Sjögren's syndrome while raising risk of severe schizophrenia.
Older adults with depression may be at much higher risk of remaining depressed if they are experiencing persistent or worsening sleep problems, according to a study from researchers at Johns Hopkins Bloomberg School of Public Health.
A study led by Boston Children's Hospital and Massachusetts General Hospital demonstrates that a predictive computer model can identify patients at risk for attempting suicide from patterns in their electronic health records -- an average of two years ahead of time.
In a recent study published in the Journal of Developmental & Behavioral Pediatrics, Stewart H. Mostofsky, M.D., director of the Center for Neurodevelopmental and Imaging Research at Kennedy Krieger Institute, and Karen E. Seymour, Ph.D., assistant professor of Psychiatry and Behavioral Sciences at Johns Hopkins University School of Medicine, found that a mindful movement (Tai-Chi)-based training intervention was associated with significant improvements in school-age children with ADHD and improved their ability to regulate hyperactive, impulsive and inattentive behavior.
Cannabis use makes young brains more sensitive to the first exposure to cocaine, according to a new study on rodents led by scientists at Columbia University and the University of Cagliari in Italy. By monitoring the brains of both adolescent and adult rats after giving them synthetic psychoactive cannabinoids followed by cocaine, the research team identified key molecular and epigenetic changes that occurred in the brains of adolescents -- but not adults.
Scientists at the Icahn School of Medicine at Mount Sinai have discovered a new role for the brain chemical dopamine that is independent of classic neurotransmission. The new role appears to be critical to changes in gene expression related to chronic exposure to, or abuse of, cocaine, according to a study published Friday, April 10, 2020 in the journal Science.
People who have survived a suicide attempt are less sensitive to bodily signals related to their heart and breath, and have a higher tolerance for pain, suggest new findings published today in eLife.