Public Release: 16-Jul-2020

Science
Researchers discover 2 paths of aging and new insights on promoting healthspan
Scientists have unraveled key mechanisms behind the mysteries of aging. They isolated two distinct paths that cells travel during aging and engineered a new way to genetically program these processes to extend lifespan. Cells embark upon either a nucleolar or mitochondrial path early in life, and follow this "aging route" throughout their entire lifespan through decline and death. At the heart of the controls the researchers found a master circuit that guides these aging processes.

National Institutes of Health-National Institute on Aging, National Science Foundation Molecular and Cellular Biosciences and UC San Diego Cellular and Molecular Genetics training program.