WILLIAMSTOWN, Mass.--The National Science Foundation has awarded a grant of $266,191 to Nancy Roseman, assistant professor of biology, for her work on deoxyuridine triphosphatase (dUTPase), an enzyme involved in DNA metabolism.
Roseman uses the vaccinia virus as a model to understand viral/host interactions and to study the biochemistry of dUTPase. Because the vaccinia enzyme is very similar to its human homologue, it is an excellent system in which to study the dUTPase enzyme. The dUTPase enzyme provides a precursor for DNA replication.
Roseman, who has taught at Williams since 1991, teaches courses on immunology, biochemistry, introductory biology, virology, and the molecular biology of HIV. Her papers have been published by the American Society of Virology, the Proceedings of the National Academy of Sciences, Virology, and the Journal of Biological Chemistry.
She is the co-author with Daniel Lynch, associate professor of biology and chair of the biology department, of a question and solution manual for a new introductory biology textbook.
She received her A.B. from Smith College in 1980 and her Ph.D. from Oregon State University in 1987.