Obesity is more prevalent among African Americans than among Caucasians. In a retrospective study of 447 African American subjects published in The American Journal of Clinical Nutrition, Stettler et al. compared data collected at birth with measurements of adiposity taken in early adulthood. Among 9 potential independent birth variables, 3 were strongly associated with adult obesity: first-born status, female sex, and the mother's prepregnancy body mass index.
The potential independent birth variables included sex, birth weight for gestational age, placental weight, birth order, maternal prepregnancy body mass index (BMI), maternal pregnancy weight gain, maternal education, presence of the father in the household, and the number of adults living in the household at enrollment. Height and weight measurements of the offspring were taken when they were between the ages of 18.0 and 22.9. The skinfold thickness method was used to determine fatness, which is considered a more direct indicator of adiposity than the BMI calculation.
Twelve percent of the risk for obesity could be accounted for by first-born status, female sex, and mother's prepregnancy weight, the greatest effect being due to first-born status. Most of the variability in fatness was associated with unmeasured factors -- either those present at birth which were not measured, or postnatal lifestyle factors such as diet and physical activity. An accompanying editorial by Dietz emphasizes that, of the 3 identified risk factors for obesity, only the mother's prepregnancy weight is modifiable. It is important that evidence-based preventive strategies aimed toward establishing healthy lifestyles be focused on modifiable risks.
Stettler, Nicolas et al. Early risk factors for increased adiposity: a cohort study of African American subjects followed from birth to young adulthood. Am J Clin Nut 2000;71:378-83.
Dietz, William H. Birth weight, socioeconomic class, and adult adiposity among African Americans. Am J Clin Nut 2000;71:335-6.
For more information please contact Dr. Nicolas Stettler at nstettle@cceb.med.upenn.edu
This media release is provided by The American Society for Clinical Nutrition, to provide current information on nutrition-related research. This information should not be construed as medical advice. If you have a medical concern, consult your doctor.
To see the complete text of this article, please go to:
http://www.faseb.org/ascn/temp/ajcn/August/378-383-stettler1.pdf
To see the editorial by Dietz, please go to:
http://www.faseb.org/ascn/temp/ajcn/August/11890-Dietz.pdf
To see the editorial by Dietz, please go to:
http://www.faseb.org/ascn/temp/ajcn/August/11890-Dietz.pdf
Journal
American Journal of Clinical Nutrition