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American Chemical Society's Weekly PressPac -- Aug. 8, 2007

American Chemical Society


IMAGE: A cataract is a clouding of the lens in the eye that affects vision. Most cataracts occur in older persons. By age 80, more than half of all people... view more

Credit: (Courtesy of NIH/National Eye Institute)

Here is the latest American Chemical Society (ACS) News Service Weekly PressPac with news from ACS' 35 peer-reviewed journals and Chemical & Engineering News.

Please credit the individual journal or the American Chemical Society as the source for this information.

ACS NEWS SERVICE -- Aug. 8, 2007 Weekly PressPac -- ALL CONTENT IS FOR IMMEDIATE USE EXCEPT ARTICLE #5, which is embargoed for 9 A. M., Eastern Time, August 15, 2007.

NOTE TO JOURNALISTS: Special editions of the Aug. 15 and Aug. 22 PressPac will carry breaking science news from the ACS National Meeting in Boston.

PressPac Archive:

News Items in This Edition:

  • Toward prevention of a common complication of cataract surgery
  • Easing concerns about a promising new medical imaging agent
  • Explosive discovery on genetically engineered tobacco plant
  • Fast, accurate sensor to detect food spoilage
  • Toward real-world Star Trek tricoder devices

Mark Your Calendars:

  • 234th ACS National Meeting, August 19-23, Boston, MA

For Wired Readers:

  • Science Elements: A New ACS Podcast
  • YouTube Videos: It's Alive!!
    Scientists Invade Boston

Journalists' Resources:

  • New ACS Annual Report
  • Sustainability Pledge from World's Top Chemical Societies
  • Special PressPac Editions for ACS National Meeting
  • Chemistry Glossary

PressPac information is intended for your personal use in news gathering and reporting and should not be distributed to others. Anyone using advance PressPac information for stocks or securities dealing may be guilty of insider trading under the federal Securities Exchange Act of 1934.


Toward prevention of a common complication of cataract surgery

A newly developed method for coating the intraocular lenses (IOLs) used in millions of cataract surgery procedures may prevent a common complication of cataract surgery, according to a report scheduled for the Aug. 13 issue of ACS' Biomacromolecules, a monthly journal. Such surgery corrects the vision loss that occurs when the lens of the eye becomes clouded.

Christine Jérôme and colleagues report development of a method for applying a polyethylene glycol coating to IOLs. In laboratory experiments, researchers showed that the coating reduced accumulation of the protein film and adhesion of cells responsible for formation of secondary cataracts. The coating did not affect the optical properties of the lens. It also could be applied to certain other surfaces in order to discourage undesirable protein accumulation and adhesion of cells, the report states.

During the operation, a small incision in the front of the lens capsular bag is used to remove the clouded crystalline lens. The IOL is inserted into the empty capsular bag. Researchers noted that IOL replacement surgery is a safe and well-established procedure to correct the vision loss from a cataract. In about 25 percent of cases, however, the back portion of the capsule eventually becomes clouded with a "secondary" cataract. Jérôme notes that treatment is available for secondary cataracts, but describes it as risky

ARTICLE #1 FOR IMMEDIATE RELEASE "Improved Performances of Intraocular Lenses by Poly(ethylene glycol) Chemical Coatings"


Christine Jérôme, Ph.D.
University of Liege
Liege, Belgium
Phone: 32-4-3663491
Fax: 32-4-3663497


Easing concerns about a promising new medical imaging agent
Chemical Research in Toxicology

In a study that eases concern about the toxicity of nanoparticles being considered for use in medical imaging and biomedical research, scientists in North Dakota are reporting "no significant toxic effects" from tests of silica nanoparticles. It is scheduled for the Aug. 20 issue of ACS' Chemical Research in Toxicology, a monthly journal.

Min Wu and Julia Xiaojun Zhao and colleagues point out that scientists hope to use several kinds of nanomaterials that luminesce, or glow, in clinical medicine and biomedical research. Those materials might, for instance, become a new generation of imaging agents that pinpoint the location of diseased tissue in the body. "However, the question of whether these nanomaterials are toxic to living cells or organisms has not been fully answered," the researchers explain.

The scientists used laboratory tests on human lung cells to show that luminescent silica nanoparticles did not damage cellular DNA. "Our study indicates that the luminescent silica nanoparticle is a promising labeling reagent for various biomedical applications," the study concluded, citing the need for further research on potential long-term toxicity.

ARTICLE #2 FOR IMMEDIATE RELEASE "Toxicity of Luminescent Silica Nanoparticles to Living Cells"


Min Wu, Ph.D.
University of North Dakota
Grand Forks, North Dakota 58202
Phone: 701-777-3610
Fax: 701-777-2331

Julia Xiaojun Zhao, Ph.D.
Phone: 701-777-3610
Fax: 701-777-2331


Explosive discovery on genetically engineered tobacco plant
Environmental Science & Technology

Tobacco may be bad for human health, but a new study reports that a genetically engineered tobacco plant may be very good for the environment. It shows promise for cleaning up soil contaminated with TNT, a widely used military explosive. The study is scheduled for the Aug. 15 issue of ACS' Environmental Science & Technology, a semi-monthly journal.

Neil C. Bruce and colleagues noted that TNT contamination is a major environmental problem at many World War II sites, military training areas, and explosive manufacturing sites. In addition to being explosive, TNT is toxic and a human health threat. Researchers knew that certain soil bacteria could metabolize and change trinitrotoluene (TNT) into nontoxic compounds. But those natural bacteria exist at levels too low to detoxify TNT.

In the new study, researchers inserted a gene for a TNT-transforming bacterial enzyme into a tobacco plant. Then they tested the plant's effect on TNT-contaminated soil in comparison to regular tobacco plants grown in the same soil for several weeks. The genetically modified plants significantly reduced the toxicity of the TNT-contaminated soil.

"This is the first report to demonstrate that transgenic plants engineered for the phytoremediation of organic pollutants can increase the functional and genetic diversity of the bacterial community in acutely polluted soil compared to wild type plants," the report states. "Our findings have important implications, not only for use of genetically engineered plants for TNT remediation, but for cleaning up other sources of contamination as well."

ARTICLE #3 FOR IMMEDIATE RELEASE "Impact of Transgenic Tobacco on Trinitrotoluene (TNT) Contaminated Soil Community"


CONTACT: Neil C. Bruce, Ph.D.
University of York
United Kingdom
Phone: 44-1904-32877


Fast, accurate sensor to detect food spoilage
Organic Letters

Amid growing concern about outbreaks of food poisoning, researchers in South Carolina are reporting development of a new "food freshness sensor," for fast, accurate detection of food spoilage. Their study is scheduled for the Aug. 16 issue of ACS' Organic Letters, a bi-weekly journal.

In the study, John Lavigne and colleagues describe the need for better sensors that can detect food spoilage caused by E. coli, Salmonella, and other disease-causing bacteria. Existing methods, such as "electronic noses" and "electronic tongues," require expensive equipment, are time consuming and involve complicated analyses.

In the study, they describe development of a polymer material that raises a red flag, changing color in the presence biogenic amines, compounds produced by the bacterial decay of food proteins. In laboratory tests, the polymer identified and distinguished between 22 different kinds of key food-spoilage amines with 97 percent accuracy. Researchers also used the polymer to check the freshness of a tuna by detecting the amount of amines present in the sample. "The sensitivity of the described assay is better than the typical mammalian sense of smell and is able to detect this nonvolatile amine at hazardous levels before the fish would begin to smell rancid," the report states. The approach also shows promise for detecting spoilage in other food types, it adds.

ARTICLE #4 FOR IMMEDIATE RELEASE "A Food Freshness Sensor Using the Multistate Response from Analyte-Induced Aggregation of a Cross-Reactive Poly(thiophene)"


John J. Lavigne, Ph.D.
University of South Carolina
Columbia, South Carolina
Phone: 803-777-2295


Toward real-world Star Trek tricoder devices
Chemical & Engineering News

So you drop by the store tonight and buy the latest model of a Star Trek tricoder-type device -- a handheld instrument for scanning alien environments -- and use it to check your home air for indoor pollutants. As farfetched as that idea may seem, such devices are inching closer to reality, according to an article ( scheduled for the August 13 issue of Chemical & Engineering News (C&EN), ACS's weekly newsmagazine.

The article, by C&EN Senior Correspondent Marc Reisch, explains that scientific instrument makers are in the midst of an effort to expand their traditional markets, moving instruments like mass spectrometers and infrared photometers out of the lab and into the hands of the average consumer. In a world that fears terrorists, contaminated food, and airborne pollutants, instrument companies are working to design portable, inexpensive, user-friendly devices that can do the work of those laboratory mainstays, Reisch writes. An executive of one major instrument maker, quoted in the article, predicts that such instruments will be available to consumers, including Star Trek-like devices that serve as personal environmental scanners.

"Given the proliferation of instruments alongside manufacturing lines and in battle zones, office buildings, and refineries, it just might be feasible for a consumer to walk into Home Depot someday and buy a device that today only a scientist or quality control expert would want to have," the article concludes.

ARTICLE #5 EMBARGOED FOR 9 A.M., EASTERN TIME, August 15, 2007 "In hot pursuit: Instrument makers harness technology to pursue budding applications for their tools"

This story will be available on August 15 at

Michael Bernstein
ACS News Service
Phone: 202-872-6042
Fax: 202-872-4370

Mark Your Calendars

234th ACS National Meeting, August 19-23, Boston, MA

News media registration is now open for the 234th ACS national meeting, which will be held in Boston, Mass., on August 19-23, 2007, at the Boston Convention and Exhibition Center and more than a dozen hotels across the city. More than 15,000 scientists and others are expected to attend this scientific extravaganza. There will be more than 9,500 presentations on new discoveries in chemistry, health, medicine, energy, environment, food, and other fields. The theme: "Biotechnology for Health and Wellness."

For Wired Readers

Science Elements: New ACS Podcast

The ACS Office of Communications is podcasting PressPac contents in order to make cutting-edge scientific discoveries from ACS journals available to a broad public audience at no charge. Science Elements includes selected content from ACS's prestigious suite of 35 peer-reviewed scientific journals and Chemical & Engineering News, ACS's weekly news magazine. Those journals, published by the world's largest scientific society, contain about 30,000 scientific reports from scientists around the world each year. The reports include discoveries in medicine, health, nutrition, energy, the environment and other fields that span science's horizons from astronomy to zoology. Podcaster for Science Elements is Steve Showalter, Ph.D., a chemist at the U. S. Department of Energy's Sandia National Laboratories in Albuquerque, New Mexico, and ACS member.

YouTube Videos

It's Alive!!!

Scientists Invade Boston

Journalists' Resources

Special PressPac Editions for ACS National Meeting PressPacs for August 15 and August 22 will be devoted to breaking news from the ACS 234th national meeting in Boston.

New ACS Annual Report The 2006 ACS annual report, A New Vision at Work, can be a valuable resource for journalists trying to keep pace with chemistry and the multiple fields of science that involve chemistry. The report features a series of commentaries by chemists, including Nobel Laureate Robert H. Grubbs, on chemistry's role in working toward better medications, more nutritious food, sources of renewable energy, and other innovations. The newly published report is available for reading and downloading at:

General Chemistry Glossary


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