In research published in this week’s PLoS Medicine, Florian Sennlaub (INSERM, Universite Pierre et Marie Curie, Paris) and colleagues show that CD36 deficiency leads to choroidal involution, a key feature of ‘”dry” age-related macular degeneration, via COX-2 down-regulation in the retinal pigment epithelium.
Citation: Houssier M, Raoul W, Lavalette S, Keller N, Guillonneau X, et al. (2008) CD36 deficiency leads to choroidal involution via COX2 downregulation in rodents. PLoS Med 5(2): e39.
PLEASE ADD THE LINK TO THE PUBLISHED ARTICLE IN ONLINE VERSIONS OF YOUR REPORT: http://medicine.plosjournals.org/perlserv/?request=get-document&doi=10.1371/journal.pmed.0050039
PRESS-ONLY PREVIEW OF THE ARTICLE: http://www.plos.org/press/plme-05-02-sennlaub.pdf
CONTACT:
Florian Sennlaub
INSERM
Universite Pierre et Marie Curie
Paris 75006
France
+33 140 467 840
sennlaub@idf.inserm.fr
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