IMGP is characterized by inflammatory granulation tissue in the lamina propria, proliferation of smooth muscle, and hyperplastic glands with variable cystic change. Only a small number of cases have been reported and the pathogenesis and natural history remain unclear.
An article to be published on August 14, 2008 in the World Journal of Gastroenterology addresses this question. The research team led by Dr. Shoji Hirasaki from Sumitomo Besshi Hospital in Japan described a relatively rare case of loburated-type IMGP in the ascending colon causing hematochezia. They also report the magnifying endoscopy findings of this IMGP.
The patient was a 33-year-old man with hematochezia. A lobulated, peduncular polyp with bleeding, about 40 mm in diameter, was found in the ascending colon at colonoscopy. Endoscopic polypectomy was performed. The histopathology of the specimen showed an IMGP. Lobulated-type IMGP in the ascending colon is rare.
In the view of the authors, the main clinical feature of colorectal IMGPs is hematochezia and endoscopic or surgical treatment is necessary if gastrointestinal bleeding occur. In this case, magnifying observation was performed before polypectomy. Magnifying endoscopy revealed a red rugged surface component, and smooth white nodules with enlarged round or oval crypt openings.
Reference: Kanzaki H, Hirasaki S, Okuda M, Kudo K, Suzuki S. Lobulated inflammatory myoglandular polyp in the ascending colon observed by magnifying endoscopy and treated with endoscopic polypectomy. World J Gastroenterol 2008; 14(30): 4838-4840
http://www.wjgnet.com/1007-9327/14/4838.asp
Correspondence to: Dr. Shoji Hirasaki, Department of Internal Medicine, Sumitomo Besshi Hospital, 3-1 Ohji-cho, Niihama 7928543, Japan. shoji_hirasaki@ni.sbh.gr.jp
Telephone: +81-897-377111 Fax: +81-897-377121
About World Journal of Gastroenterology
World Journal of Gastroenterology (WJG), a leading international journal in gastroenterology and hepatology, has established a reputation for publishing first class research on esophageal cancer, gastric cancer, liver cancer, viral hepatitis, colorectal cancer, and H pylori infection. It provides a forum for both clinicians and scientists. WJG has been indexed and abstracted in Current Contents/Clinical Medicine, Science Citation Index Expanded (also known as SciSearch) and Journal Citation Reports/Science Edition, Index Medicus, MEDLINE and PubMed, Chemical Abstracts, EMBASE/Excerpta Medica, Abstracts Journals, Nature Clinical Practice Gastroenterology and Hepatology, CAB Abstracts and Global Health. ISI JCR 2003-2000 IF: 3.318, 2.532, 1.445 and 0.993. WJG is a weekly journal published by WJG Press. The publication dates are the 7th, 14th, 21st, and 28th of every month. The WJG is supported by The National Natural Science Foundation of China, No. 30224801 and No. 30424812, and was founded with the title China National Journal of New Gastroenterology on October 1, 1995, and renamed WJG on January 25, 1998.
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World Journal of Gastroenterology