News Release

This 'mousetrap' may save lives

Rice University students create mechanism to regulate IV fluids for children

Business Announcement

Rice University

Instead of building a better mousetrap, a team of Rice University freshmen took a mousetrap and built a better way to treat dehydration among children in the developing world.

"The goal was to regulate the amount of fluid delivered to children so we could prevent over-hydration and under-hydration," said Melissa Yuan, a member of the IV DRIP (Dehydrated Relief in Pediatrics) team and a mechanical engineering major. "It's designed to be used in severely underdeveloped parts of the world, where conditions can be pretty primitive and they may not even have electricity."

The challenge that sparked the innovative design has been mentioned by physicians working in Africa since Rice's Rebecca Richards-Kortum and Maria Oden began traveling there six years ago in search of real-world design challenges for students in Rice's Beyond Traditional Borders program. Richards-Kortum is the Stanley C. Moore Professor of Bioengineering and director of Rice 360°: Institute for Global Health Technologies, which oversees Beyond Traditional Borders. Oden is a professor in the practice of engineering education and director of the Oshman Engineering Design Kitchen.

"Many times physicians have mentioned to us that they would like a tool that can better moderate IV-fluid delivery to children, who are often connected to adult IV-bags," Oden said. "In understaffed medical settings, monitoring IV-fluid delivery to patients can be a challenge. At the same time, it is of critical importance that the appropriate amount of fluid is delivered."

The device designed by the IV DRIP team is inexpensive; it costs about $20 to manufacture. It's a mechanical, durable, autonomous and simple-to-operate volume regulator that uses a lever arm with a movable counterweight similar to a physician's scale to incrementally dispense IV fluid.

The system uses the change in torque as an IV bag is drained of fluid to set off a mousetrap-like spring that clamps the IV tube and cuts off the flow of saline solution or other prescribed fluids. Tests have shown the device dispenses fluid within 12 milliliters of the desired volume in increments of 50 milliliters.

"We knew we needed something simple and reliable, not high-tech or terribly sophisticated," Yuan said. "There's nothing digital about it, nothing electrical or fancy."

The team includes chemical engineering major Paige Horton, bioengineering majors Kamal Shah and Thor Walker and mechanical engineering major Taylor Vaughn. Rebecca Hernandez, a senior in bioengineering, serves as the team's apprentice leader representing the Rice Center for Engineering Leadership.

Walker emphasized the old-fashioned engineering of the device: "There's nothing revolutionary about this thing. It was matter of determining the right weight for the steel counterweight, which is 812 grams, and calibrating everything else correctly."

The device can be mounted on a wall or attached with clamps to a portable hospital IV pole. The most time-consuming part of assembling the device was calibrating the counterweight and determining the precise spacing of the notches the counterweight falls into and holds as the fluid drains, she said.

"Then the clamp goes off and it folds the tubing in a V-shape, the way you would crimp a garden hose to make the water stop coming out," Walker said.

This summer Shah and Yuan will transport four of their prototypes to Malawi and Lesotho, respectively, to test them under practical field conditions. Malawi, in southeastern Africa, is among the least-developed countries in the world, with a high infant mortality rate and a life expectancy of about 50 years. Some 1.5 million children in developing countries die annually of dehydration.

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The device was conceived in the fall of 2011 as a freshman project in the Engineering 120, Introduction to Engineering Design course taught by Ann Saterbak, a professor in the practice of bioengineering education and director of laboratory instruction in Rice's George R. Brown School of Engineering. Team IV DRIP has already received the 2012 Willy Revolution Award for Innovation in Engineering Design, and its members will share a $2,000 prize.

In April, during the second annual National Undergraduate Global Health Technologies Design Competition hosted by Rice 360˚ and Beyond Traditional Borders, the team won the People's Choice Award for best poster. They also picked up the $500 Best Freshman Design award at the 2012 George R. Brown Engineering Design Showcase.

Rice University has a VideoLink ReadyCam TV interview studio. ReadyCam is capable of transmitting broadcast-quality standard-definition and high-definition video directly to all news media organizations around the world 24/7.

See a video demonstration at http://youtu.be/VlED86BWPcE

Related materials:

Team IV DRIP:
http://oedk.rice.edu/Content/Members/MemberPublicProfile.aspx?pageId=1137257&memberId=5551626

Rice Center for Engineering Leadership:
http://rcel.rice.edu/

George R. Brown School of Engineering:
http://engr.rice.edu/

Rice 360˚: Institute for Global Health Technologies:
http://www.rice360.rice.edu/

Beyond Traditional Borders:
http://beyondtraditionalborders.rice.edu/

Photos for download:

http://news.rice.edu/wp-content/uploads/2012/05/0511_IVRAID-1-WEB.jpg

The mechanical IV DRIP invented by students at Rice University takes cues from mousetraps for its ability to halt the flow of fluid through an intravenous line without electricity. (Credit: Jeff Fitlow/Rice University)

http://news.rice.edu/wp-content/uploads/2012/05/0511_IVRAID-2-WEB.jpg

Thor Walker attaches a line to the IV DRIP device created by a team of freshman engineering students at Rice University. A counterweight lowers as the IV bag gets lighter and trips a shutoff mechanism at the right level. (Credit: Jeff Fitlow/Rice University)

http://news.rice.edu/wp-content/uploads/2012/05/0511_IVRAID-3-WEB.jpg

Rice University freshman Melissa Yuan checks an IV bag during tests of IV DRIP, a mechanical device to regulate fluids for young patients in developing countries. (Credit: Jeff Fitlow/Rice University)

http://news.rice.edu/wp-content/uploads/2012/05/0511_IVRAID-4-WEB.jpg

Paige Horton, a freshman at Rice University, adjusts the mechanism while testing IV DRIP. The device, which regulates intravenous drips without electricity, will be tested in Africa this summer. (Credit: Jeff Fitlow/Rice University)

http://news.rice.edu/wp-content/uploads/2012/05/0511_IVRAID-5-WEB.jpg

Rice University freshmen created a device to regulate IV flow for children in developing countries. Members of the IV DRIP team (from left) are Thor Walker, Kamal Shah, Paige Horton and Melissa Yuan. (Credit: Jeff Fitlow/Rice University)

Located on a 300-acre forested campus in Houston, Rice University is consistently ranked among the nation's top 20 universities by U.S. News & World Report. Rice has highly respected schools of Architecture, Business, Continuing Studies, Engineering, Humanities, Music, Natural Sciences and Social Sciences and is known for its "unconventional wisdom." With 3,708 undergraduates and 2,374 graduate students, Rice's undergraduate student-to-faculty ratio is 6-to-1. Its residential college system builds close-knit communities and lifelong friendships, just one reason why Rice has been ranked No. 1 for best quality of life multiple times by the Princeton Review and No. 4 for "best value" among private universities by Kiplinger's Personal Finance. To read "What they're saying about Rice," go to www.rice.edu/nationalmedia/Rice.pdf.


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