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Trudeau Institute announces participation in study will advance newly discovered treatments for bacterial infections

Trudeau Institute


IMAGE: The Trudeau Institute is an independent, nonprofit, biomedical research organization, whose scientific mission is to make breakthrough discoveries leading to improved human health. view more

Credit: Trudeau Institute

Saranac Lake, New York June 11, 2012 -- The Trudeau Institute has announced it is the recipient of a sub-contract for a translational research grant from the National Institutes of Health.

This award will help the Institute move one of its discoveries closer to human trials and clinical use. It is the Institute's first small business innovation research (SBIR) grant and will fund studies in the laboratory of Dr. Stephen Smiley.

Dr. Smiley is a co-investigator on the $3,000,000 National Institute of Allergy and Infectious Diseases Advanced Technology SBIR Phase II award to Aronora, Inc. (, an Oregon-based company developing a new class of safe therapeutics for thrombotic disorders, including infections that cause blood-clotting abnormalities.

Dr. Smiley's lab will determine which types of bacterial infections respond to Aronora's new therapeutic approach.

According to Dr. Smiley, "These funds will allow us to extend our earlier collaborative work with Aronora. The prior studies showed that Aronora's therapeutic approach helps mice survive severe infections caused by Listeria, a bacterium that can cause serious human illness, especially among the elderly, the very young and those with compromised immune systems. Listeria can also cause significant complications in pregnant women, including miscarriage. The goal now is to determine whether this same approach will also work for other types of bacterial infections."

About the Trudeau Institute

The Trudeau Institute is a nonprofit biomedical research center founded in 1884 by Dr. E.L. Trudeau. The Institute's fundamental research on immunity fosters the development of vaccines, treatments and cures for many life-threatening diseases, including cancer, tuberculosis and influenza. The Institute is supported by federal and state grants and contributions from individuals, private foundations and corporations. For further information about the Trudeau Institute, go to

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