News Release

Study finds survival from cardiac arrest highest in the operating room or post-anesthesia care unit

Peer-Reviewed Publication

Michigan Medicine - University of Michigan

CHICAGO and ANN ARBOR, Mich. – A University of Michigan study from the "Online First" edition of Anesthesiology found cardiac arrest was associated with improved survival when it occurred in the operating room (O.R.) or post-anesthesia care unit (PACU) compared to other hospital locations. The findings offer evidence that the presence of anesthesia providers in these locations may improve outcomes for certain patients.

Cardiac arrest is a very uncommon complication during the perioperative period, which includes the time during and immediately after surgery and anesthesia. An estimated seven arrests occur per every 10,000 patients undergoing non-cardiac surgery each year. In the past, outcomes of cardiac arrest in the perioperative period have not been well-studied.

To better understand the management and outcomes of cardiac arrests during the perioperative period, researchers used the "Get With The Guidelines® - Resuscitation" registry, a national cardiopulmonary resuscitation registry supported by the American Heart Association. Researchers identified more than 2,500 instances of perioperative cardiac arrest from 234 hospitals.

Findings showed one in three patients survived cardiac arrest to hospital discharge. Of these patients, two of three had good brain function.

In addition, survival was approximately 25-65 percent higher if the cardiac arrest occurred in the O.R. or PACU than if it occurred in the intensive care unit (ICU) or general in-patient areas.

Researchers also found asystole, a type of cardiac arrest without electrical activity in the heart, was associated with improved survival in the O.R. and PACU compared to other hospital locations. They also found life-saving treatment was given much faster in these locations. Pulseless electrical activity (PEA), a type of cardiac arrest where the heart rhythm does not produce a pulse, was associated with worse survival to discharge in the ICU.

"The most surprising findings from our research were that very sick patients in the ICU and postoperative low-risk patients in general inpatient areas had the poorest outcomes," said Satya Krishna Ramachandran, M.D., F.R.C.A., assistant professor, Department of Anesthesiology, University of Michigan. "We found outcomes were best when cardiac arrest occurred during or immediately after surgery and anesthesia. This supports the view that the availability of anesthesia providers in the O.R. and PACU may contribute to better outcomes."

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For more information on Anesthesiology, visit anesthesiology.org.

The American Society of Anesthesiologists

Anesthesiologists: Physicians providing the Lifeline of Modern Medicine™. Founded in 1905, the American Society of Anesthesiologists is an educational, research and scientific association with more than 50,000 members organized to raise and maintain the standards of the medical practice of anesthesiology and improve the care of the patient.

For more information on the field of anesthesiology, visit the American Society of Anesthesiologists website at asahq.org. For patient information, visit LifelinetoModernMedicine.com.

The University of Michigan Health System

For more than 160 years, the U-M Health System has been a national leader in advanced patient care, innovative research to improve human health and comprehensive education of physicians and medical scientists. UMHS includes the U-M Hospitals & Health Centers, with its three hospitals and dozens of outpatient health centers and clinics throughout Michigan; the U-M Medical School with its Faculty Group Practice and research laboratories; shared administrative services; and the Michigan Health Corporation. The three U-M hospitals -- University Hospital, C.S. Mott Children's Hospital, and Von Voigtlander Women's Hospital – have been recognized numerous times for excellence in patient care, including 17 years on the U.S. News & World Report honor roll of "America's Best Hospitals". The U-M Medical School is one of the nation's biomedical research powerhouses, with total research funding of more than $490 million. Together, the 22,000 members of the UMHS community are creating the future of health care through discovery.


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