When repairing nerves with adhesives, most researchers place glue directly on the nerve stumps, but this method does not fix the nerve ends well and allows glue to easily invade the nerve ends. Ordinarily, nerve conduits are cylindrical. However, it is difficult to insert the nerve ends into the conduit because the nerve is soft and there is frictional resistance. Xiangdang Liang and co-workers from the General Hospital of Chinese PLA designed a special conduit for the adhesive technique and defined the best parameters for its use through in vitro testing, and then repaired nerves with cyanoacrylate and the modified conduit in an in vivo rat model. This adhesive method for repairing nerves using a modified conduit is feasible and effective, and reduces the operation time while providing an equivalent repair effect. The relevant article has been published in the Neural Regeneration Research.
Article: " Sciatic nerve repair using adhesive bonding and a modifed conduit," by Xiangdang Liang1, Hongfei Cai1, Yongyu Hao2, Geng Sun3, Yaoyao Song1, Wen Chen1 (1 Department of Orthopedics, General Hospital of Chinese PLA, Beijing, China; 2 Wei Zikeng Clinic of General Armament Department of Chinese PLA, Beijing, China; 3 Department of Orthopedics, 252 Hospital of Chinese PLA, Hebei Province, China)
Liang XD, Cai HF, Hao YY, Sun G, Song YY, Chen W. Sciatic nerve repair using adhesive bonding and a modified conduit. Neural Regen Res. 2014;9(6):594-601.