News Release

Low-carb vs. low-fat diets

Annals of Internal Medicine tip sheet for Sept. 2, 2014

Peer-Reviewed Publication

American College of Physicians

1. Low-carb trumps low-fat for weight loss and cardiovascular risk

Free Summary for Patients http://www.annals.org/article.aspx?doi=10.7326/P14-9029

A low-carbohydrate diet is more effective for weight loss and reducing cardiovascular risk factors than a low-fat diet, according to an article being published in Annals of Internal Medicine. More than one third of American adults have at least one form of cardiovascular disease and cardiovascular disease causes one third of all deaths. Low-carbohydrate diets are a popular strategy for weight loss, but their cardiovascular effects are unknown, especially among diverse populations. To compare the effects of a low-carbohydrate versus a low-fat diet on body weight and cardiovascular risk factors, researchers randomly assigned 148 men and women without clinical cardiovascular disease and diabetes to follow a low-carbohydrate (less than 40g a day) or low-fat diet (less than 30 percent of daily calories from fat). All participants were classified as obese based on body mass index and just over half of the participants were black. Both the low-carbohydrate and the low-fat groups received dietary counseling at regular intervals but had no specific calorie or energy goals. At one year, both black and white participants on the low-carbohydrate diet had greater decreases in weight, fat mass, and other cardiovascular risk factors than those on the low-fat diet.

Note: The URL will be live at 5:00 p.m. on Monday, September 1 and can be included in news stories. For a PDF, please contact Megan Hanks. To interview the lead author, please contact Keith Brannon at kbrannon@tulane.edu or 504-862-8789.

2. Rise in obesity is a substantial contributor to increased prevalence of diabetes

An increase in body mass index (BMI) over time is the most important factor contributing to the observed increase in diabetes prevalence since 1976, according to a study being published in Annals of Internal Medicine. Diabetes is one of the most common and costly chronic disorders in the United States. Researchers analyzed data from five National Health and Nutrition Examination Surveys to determine the extent to which the increase in diabetes prevalence is explained by changing distributions of race/ethnicity, age, and obesity prevalence in U.S. adults. They found that the prevalence of diabetes nearly doubled from 1976 to 1980 and also from 1999 to 2004. During both time periods, diabetes prevalence increased more in men than in women. The increase of certain risk factors, including BMI, race and ethnicity, and age, coincided with an increased incidence of diabetes, with BMI being the greatest contributor among the three covariates. The researchers suggest that public health efforts should focus on interventions that address obesity. The increased prevalence of diabetes among men could not be explained by an increased BMI in men. Researchers suggest that future research should investigate what additional factors may contribute to the faster rise in diabetes in men than in women.

Note: The URL will be live at 5:00 p.m. on Monday, September 1 and can be included in news stories. For a PDF, please contact Megan Hanks. The lead author, Dr. Andy Menke, can be contacted directly at AMenke@s-3.com or 301-628-0331.

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