Puerarin is a natural isoflavone isolated from plants of the genus Pueraria and functions as a protector against cerebral ischemia. Can puerarin be involved in the repair of peripheral nerve injuries? Minfei Wu and co-workers from the Second Hospital of Jilin University in China verified that puerarin exerts an ongoing role to activate growth-associated protein 43 in the corresponding segment of the spinal cord after sciatic nerve injury, thus contributing to neural regeneration after sciatic nerve injuries. Their relevant study has been reported in the Neural Regeneration Research.
"Puerarin accelerates neural regeneration after sciatic nerve injury," by Minfei Wu1, Guanjie Zhao2, Xiaoyu Yang1, Chuangang Peng1, Jianwu Zhao1, Jun Liu1, Rui Li3, Zhongli Gao1 (1 Department of Orthopedics, China-Japan Union Hospital of Jilin University, Changchun, Jilin Province, China; 2 Department of Nephropathy, China-Japan Union Hospital of Jilin University, Changchun, Jilin Province, China; 3 Hand & Foot Surgery and Reparative & Reconstruction Surgery Center, the Second Hospital of Jilin University, Changchun, Jilin Province, China)
Wu MF, Zhao GJ, Yang XY, Peng CG, Zhao JW, Liu J, Li R, Gao ZL. Puerarin accelerates neural regeneration after sciatic nerve injury. Neural Regen Res.2014;9(6):589-593.
Neural Regeneration Research