Public Release: 

Mechanical ventilation a key indicator for pre-term children's math problems

University of Warwick


IMAGE: This is Professor Dieter Wolke, University of Warwick. view more

Credit: University of Warwick

A new study, led by researchers at the University of Warwick in the UK and the Ruhr-University Bochum in Germany, and just published in the Journal Early Human Development, has found that both the length of time spent in hospital after birth and the use of mechanical ventilation are key indicators of reduced mathematical ability in preterm children.

Mathematic abilities are crucial for lifelong academic attainment. Impairments in mathematic abilities are common in very preterm children. Earlier studies of children who are born very preterm (before 32 weeks of gestational age) have shown that they have a 39.4% chance of having general mathematic impairment, compared to 14.9% of those born at term (39 to 41 weeks). This may be due to the fact that mathematic performance requires simultaneous processing of complex information which is particularly compromised in preterm children.

This latest study, led by Dr Julia Jaekel and Professor Dieter Wolke, found that preterm children's specific mathematic abilities decrease exponentially with lower gestational age.

However, the study also establishes two significant individual key indicators of future mathematic problems for preterm children; the duration of neonatal medical treatment in hospital immediately after birth and the use of mechanical ventilation.

The researchers used path analyses to establish two neurodevelopmental cascade models. Their findings are based on the fact that, on average, a healthy full term child had a general maths score of 100, a specific maths score of 101 and was never ventilated. In contrast, a very preterm child, on average, had a general maths score of 88, a specific maths score of 97 and was ventilated for 17 days.

A total of 51 very preterm children were ventilated longer than 30 days (thus the highest risk group) and these, on average, had a general maths score of 73 and a specific maths score of 91.

Dr Julia Jaekel, from both the University of Warwick's Department of Psychology, and the Ruhr-University Bochum said:

"It is difficult to see how one could reduce the duration of neonatal medical treatment, as this may relate to a number of medical needs. However there are now less invasive options to mechanical ventilation as the adverse effects on brain development are well known. Future studies will have to show if the less invasive treatment of new generations of preterm children may also have decreased their risk for specific impairments in mathematic tasks."

"Our findings may have significant implications for the choice of mode of respiratory support in neonates."


Notes for editors:

The research received funding from the German Research Foundation (DFG) and the German Federal Ministry of Education and Science (BMBF). The contents and conclusions of the research are solely the responsibility of the authors and do not represent the official views of the DFG or the BMBF.

The paper has just been published in the Journal Early Human Development and is entitled: Neurodevelopmental pathways to preterm children's specific and general mathematic abilities. The full list of authors is: Julia Jaekel (University of Warwick and the Ruhr-University Bochum); Professor Dieter Wolke (University of Warwick), Peter Bartmann (Institute of Neonatology, University Hospital Bonn); and Wolfgang Schneider (Department of Psychology, University of Würzburg).

For further information please contact:

Dr Julia Jaekel,

University of Warwick in the UK, and the Ruhr-University Bochum in Germany

Direct telephone number also available. Please contact International Press Officer Tom Frew -

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