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Drug-loaded beads may help treat liver cancer

Wiley

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IMAGE: This is a fluorescent micrograph showing the complete loading of idarubicin 10 mg in 2 mL DC Bead 300-500 μm. At the drug/beads contact time, the blue beads were distinguishable... view more

Credit: Alimentary Pharmacology and Therapeutics

A new phase 1 safety trial has demonstrated that idarubicin-loaded beads are well tolerated by patients but are toxic to liver cancer cells. Idarubicin is an anthracycline that is currently used to treat leukemias.

Two months into the 21-patient trial, the tumors of 28% of patients had complete responses to the drug, and the tumors of 24% of patients had a partial response. The findings are published in Alimentary Pharmacology and Therapeutics.

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