Bethesda, MD - The FASEB Science Research Conference on Mobile DNA In Mammalian Genomes is focused on the remarkably dynamic nature of mammalian genomes and the phenotypic impact thereof. Topics will include both mechanistic and evolutionary aspects of a wild jumble of diverse retrotransposons, endogenous retroviruses and DNA transposons, as well as their interactions with the epigenome and endogenous machinery of DNA repair and rearrangement. These elements are not just a major genome component but also a significant contributor to genomic diversity in the form of structural variation, increasingly recognized as a major contributor to human genetic disease. While the germ line is a well-known hotbed of activity of mobile genetic elements, there is increasing evidence for mobility in normal mammalian soma such as stem cells and neuronal tissues, as well as in cancer, autoimmune diseases and aging. Moreover, new insights are being gained into the role of mobile elements in shaping gene regulatory networks, particularly in stem cells. Finally, engineering of mobile elements as tools has provided new abilities to manipulate and query mammalian and other genomes. Due to their activity in stem cells, and as regenerative medicine, enters the realm of clinical reality, it becomes critical to understand and control mechanisms of genome variation, which can have unpredictable negative consequences on stem cell products to be used for therapy.
A significant number of oral presentations will be selected from the abstracts, and the selected talks, poster presentations, and recreational activities will provide students and postdoctoral fellows opportunities to exchange ideas and formulate new collaborations.
FASEB has announced a total of 34 Science Research Conferences (SRC) in 2015. Registration opens January 20, 2015. For more information about an SRC, view preliminary programs, or find a listing of all our 2015 SRCs, please visit http://www.
Since 1982, FASEB SRC has offered a continuing series of inter-disciplinary exchanges that are recognized as a valuable complement to the highly successful society meetings. Divided into small groups, scientists from around the world meet intimately and without distractions to explore new approaches to those research areas undergoing rapid scientific changes.
Contact: Robin Crawford, CMP
Office of Scientific Meetings & Conferences
MOBILE DNA IN MAMMALIAN GENOMES
Date: June 14 - 19, 2015
Marriott West Palm Beach, West Palm Beach, FL
Organizers: Jef Boeke, Dixie Mager, Zsuzsanna Izsvak,
Zoltan Ivics, Kathleen Burns, Jose Garcia-Perez