Bethesda, MD - Eukaryotic DNA is several meters long and must be packaged into chromatin in a way that enables the RNA Polymerase II (Pol II) machinery to access the genes during development and differentiation. We still possess only rudimentary knowledge of the packaging of the genome and how the transcriptional machinery and its regulatory factors interact with the gene-coding and non-coding sequences. Yet, this process underlies all gene expression, which is fundamental to development and differentiation. Eukaryotic RNA Polymerase II (RNA Pol II), chromatin, and its posttranslational modifications play a pivotal role in regulating gene expression. Our genome encodes more than 30,000 distinct proteins and many more non-coding RNAs. A central challenge to current research is to determine how the synthesis of messenger RNA and non-coding RNA by RNA Polymerase II is coordinated, resulting in proper development and cellular regulation. Given the implications of defining the molecular mechanisms of gene expression by chromatin and RNA Pol II, and its impact on our understanding of cellular development and disease pathogenesis, FASEB is bringing together investigators from variously related areas of research for a focused meeting titled, "Transcriptional Regulation by Chromatin and RNA Polymerase II."
A large number of oral presentations will be selected from the abstracts, and the selected talks, poster presentations, and recreational activities will provide students and postdoctoral fellows opportunities to exchange ideas and formulate new collaborations.
FASEB has announced a total of 34 Science Research Conferences (SRC) in 2015. Registration opens January 20, 2015. For more information about an SRC, view preliminary programs, or find a listing of all our 2015 SRCs, please visit http://www.
Since 1982, FASEB SRC has offered a continuing series of inter-disciplinary exchanges that are recognized as a valuable complement to the highly successful society meetings. Divided into small groups, scientists from around the world meet intimately and without distractions to explore new approaches to those research areas undergoing rapid scientific changes. In efforts to expand the SRC series, potential organizers are encouraged to contact SRC staff at SRC@faseb.org. Proposal guidelines can be found at http://www.
FASEB is composed of 27 societies with more than 120,000 members, making it the largest coalition of biomedical research associations in the United States. Our mission is to advance health and welfare by promoting progress and education in biological and biomedical sciences through service to our member societies and collaborative advocacy.
Federation of American Societies for Experimental Biology
9650 Rockville Pike, Bethesda, MD 20814-3998
TRANSCRIPTION, CHROMATIN AND EPIGENETICS
Date: June 28 - July 3, 2015, West Palm Beach, FL
Organizers: Ali Shilatifard, Luciano Di Croce, Ramin Shiekhattar, Shelley Berger, Robert Kingston, Tony Kouzarides