Public Release: 

FASEB Science Research Conference: Regulation and Function of Small GTPases

Federation of American Societies for Experimental Biology

Bethesda, MD - This FASEB SRC on the 'Regulation and Function of Small GTPases' is the twelfth in a series devoted to the topic over the last 23 years. Small GTP-binding proteins regulate diverse cellular processes including proliferation, migration, development, gene expression, and vesicular trafficking. Deregulation of small GTPases and their downstream effector pathways is important in oncogenesis, as well as metabolic, vascular and developmental disorders. The historical strength of this meeting lies in its focus on unravelling complex signal transduction pathways and using state-of-the art technologies and refined model systems.

The 2015 meeting will provide an interdisciplinary scientific environment that brings together individuals that work on different GTPases and utilize different scientific approaches: biochemistry, cell biology, mouse models, systems biology, functional genomics, computational biology and membrane biophysics. Translational discoveries and progress in GTPase-directed therapeutics will be highlighted. Whilst there is a prominent cancer theme, the conference will provide mechanistic insight into the operation of GTPases in many biological systems. This meeting is the only forum that brings together an international group of researchers with signal transduction and cell biological expertise with investigators that the study the biology of pathway deregulation in cancer and developmental models.

A large number of oral presentations will be selected from the abstracts, and the selected talks, poster presentations, and recreational activities will provide established scientists, students and postdoctoral fellows opportunities to exchange ideas and formulate new collaborations. To foster the development of the next generation of researchers there will also be a series of formal mentoring and networking sessions. We anticipate providing some student and postdoc travel scholarships for the meeting.

FASEB has announced a total of 34 Science Research Conferences (SRC) in 2015. Registration opens January 20, 2015. For more information about an SRC, view preliminary programs, or find a listing of all our 2015 SRCs, please visit


Since 1982, FASEB SRC has offered a continuing series of inter-disciplinary exchanges that are recognized as a valuable complement to the highly successful society meetings. Divided into small groups, scientists from around the world meet intimately and without distractions to explore new approaches to those research areas undergoing rapid scientific changes.

In efforts to expand the SRC series, potential organizers are encouraged to contact SRC staff at Proposal guidelines can be found at

FASEB is composed of 27 societies with more than 120,000 members, making it the largest coalition of biomedical research associations in the United States. Our mission is to advance health and welfare by promoting progress and education in biological and biomedical sciences through service to our member societies and collaborative advocacy.

Federation of American Societies for Experimental Biology
9650 Rockville Pike, Bethesda, MD 20814-3998

Date: June 7-12, 2015, West Palm Beach, FL
Organizers: John Hancock, Heidi Welch

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