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Inflammatory markers linked with an increased risk of premature death in adults with COPD


Chronic obstructive pulmonary disease, or COPD, is characterized by a state of inflammation. A new Respirology study has identified certain inflammatory markers that can be used to predict which patients are at the highest risk of dying prematurely.

In a national sample of 1144 US adults who were followed from 1988 to 2006, those with obstructive lung function had higher levels of white blood cell count and fibrinogen as well as a higher percentage of elevated C-reactive protein than participants with normal lung function. White blood cell count and concentrations of elevated C-reactive protein were weakly associated with an increased risk of dying during follow-up. Elevated concentrations of fibrinogen were modestly linked with an increased risk of dying.


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