News Release

Global expansion of hepatitis vaccination needed to progress hepatitis B elimination

Expansion of existing interventions could prevent 13 million deaths due to hepatitis B

Peer-Reviewed Publication

European Association for the Study of the Liver

April 23, 2015, Vienna, Austria: Results revealed today at The International Liver Congress™ 2015 demonstrate current treatment and prevention programmes need to be scaled up in order to make elimination of hepatitis B virus (HBV) possible.

The study conducted by Imperial College Scientists, highlights that if existing interventions, such as infant hepatitis B vaccination and treatment programmes, were scaled up, the number of new chronic HBV infections could be reduced by 90% and mortality levels could be reduced by 65% by 2030. Globally, this would mean 13 million deaths could be prevented, including 6 million cancer cases.

Although universal infant vaccination programmes have proved successful in decreasing the number of new HBV infections, without further intervention the study estimates that the number of people infected with HBV will remain at the current level for the next 40 to 50 years, resulting in 20 million deaths by 2030.

The results were generated using a mathematical model of the worldwide HBV epidemic, which incorporated data on epidemiology, vaccination coverage, treatment, regional demography and the natural history of the virus. Predictions for incidence of new chronic infections, prevalence and HBV-related mortality were developed for interventions remaining at current levels. The researchers then explored what scaling up of treatment and prevention would be needed to achieve control and elimination of HBV by 2030.

The study highlights the need to increase current levels of interventions, including the expansion of vaccination and treatment programmes, in order to significantly reduce the transmission of HBV and lower mortality.

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About The International Liver Congress™

This annual congress is the biggest event in the EASL calendar, attracting scientific and medical experts from around the world to learn about the latest in liver research. Specialists share research studies and findings, and discuss the hottest topics related to liver disease. This year, the congress is expected to attract approximately 10,000 delegates from all corners of the globe. 2015 is a very special year for EASL and the hepatology community as they will celebrate the 50th annual meeting. The International Liver Congress™ takes place from April 22-26, 2015, Vienna, Austria.

About EASL

Since EASL's foundation in 1966, this not-for-profit organisation has grown to over 4,000 members from more than 100 countries around the world. EASL is the leading liver association in Europe, it attracts the foremost hepatology experts and has an impressive track record in promoting research in liver disease, supporting wider education and promoting changes in European liver policy.

Contact

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