NEW BRUNSWICK, N.J. - The National Institute of Neurological Disorders and Stroke (NINDS) has awarded a five-year U24 grant worth up to $6,034,323 to RUCDR Infinite Biologics, a unit of Rutgers' Human Genetics Institute of New Jersey. RUCDR, which is located on Rutgers' Busch Campus in Piscataway, is the world's largest university-based biorepository.
With the new grant, the Rutgers operation will take over management of the NINDS stem cell repository. RUCDR also will provide a comprehensive range of stem-cell related services including derivation and quality control of induced Pluripotent Stem Cells (iPSCs), to researchers throughout the world investigating diseases including Parkinson's, amyotrophic lateral sclerosis (ALS), and Huntington's. These scientists will therefore have greater access to high quality stem cells and other biospecimens that are essential to their work, according to Jay Tischfield, CEO and founder of RUCDR Infinite Biologics and the Duncan and Nancy Macmillan Distinguished Professor of Genetics at Rutgers.
"Under this new grant from NINDS, we will be utilizing innovative technologies, including molecular characterization of stem cell pluripotency and genomic stability, to provide the highest quality cell lines and data to advance discovery in areas of focus for NINDS," Tischfield said. "We also will use cutting-edge methods such as CRISPR-based systems to edit the genomes of induced pluripotent stem cells, generating powerful tools for research into the genetic causes and correlates of nervous system disorders."
RUCDR has been providing genomic services to NIH-funded researchers since 1998 and stem cell services since 2011, including management of the National Institute of Mental Health (NIMH) Stem Cell Center and the iPSC collection of the NIH Center for Regenerative Medicine.
About RUCDR Infinite Biologics - RUCDR Infinite Biologics offers a complete and integrated selection of biological sample processing, analysis, and biorepository services to government agencies, academic institutions, foundations, and biotechnology and pharmaceutical companies within the global scientific community. RUCDR provides DNA, RNA, and cell lines with clinical data to hundreds of research laboratories for studies on mental health and developmental disorders, drug and alcohol abuse, diabetes and digestive, liver, and kidney diseases. A unit of Rutgers' Human Genetics Institute of New Jersey, RUCDR is the world's largest university-based biorepository. RUCDR created the Bioprocessing Solutions Alliance, a state-of-the-art scientific and technology infrastructure for the delivery of advanced sample bioprocessing and biobanking solutions, with business partner BioStorage Technologies in 2012.
About Rutgers - Rutgers, The State University of New Jersey, is a leading national research university. Established in 1766 and celebrating a milestone 250th anniversary in 2016, the university is the eighth oldest higher education institution in the United States. More than 66,000 students and 22,000 faculty and staff learn, work, and serve the public at Rutgers locations across New Jersey and around the world. Rutgers-New Brunswick is the only public institution in New Jersey represented in the prestigious Association of American Universities. Rutgers also is a member of the Big Ten Conference and its academic counterpart, the Committee on Institutional Cooperation, a consortium of 15 world-class research universities. Rutgers is among the top 30 universities nationally for total R&D funding. The Office of Research and Economic Development is a central point for industry to access Rutgers and offers a website designed for business people: businessportal.rutgers.edu.