Public Release: 

Biological methylation: Fundamental mechanisms in health and disease

Federation of American Societies for Experimental Biology

Bethesda, MD - This SRC is focused on the role of Methylation Dynamics in nuclear and cytoplasmic biological processes and how this modification impacts development, epigenetic cellular identity, tissue homeostasis and disease. Studies looking at how this chemical modification impacts nucleic acid and protein function across model systems and in disease models will be presented. These topics will be complemented with presentations on how methylation states are established, maintained, interpreted and inter-converted, along with their functional cellular consequences and how this translates into developmental and disease states. Since methylation has become a major therapeutic target in recent years, there will be a focus on the advancements in therapeutics and technologies used to quantitatively monitor this modification in cells and organisms.

This meeting will bring together an interdisciplinary group of scientists interested in how a small covalent modification can have such profound biological impact. Invited speakers are experts in biological methylation from a variety of perspectives including cell and developmental biology, molecular biology, epigenetics/epigenomics, structural biology and chemical biology. The conference will be structured to optimize interactions among all attendees, with several poster sessions and technology workshops. A significant number of oral presentations will be chosen from poster abstracts submitted by trainees and junior faculty. This conference will also be an excellent opportunity for scientists less familiar with methylation mediated signaling and epigenetics to learn how this rapidly evolving field could impact their research.

FASEB has announced a total of 36 Science Research Conferences (SRC) in 2016. Registration opens January 7, 2016. For more information about an SRC, view preliminary programs, or find a listing of all our 2016 SRCs, please visit


Date: June 19-24, 2016, Lisbon, Portugal
Organizers: Cheryl Arrowsmith, Johnathan Whetstine

Since 1982, FASEB SRC has offered a continuing series of inter-disciplinary exchanges that are recognized as a valuable complement to the highly successful society meetings. Divided into small groups, scientists from around the world meet intimately and without distractions to explore new approaches to those research areas undergoing rapid scientific changes. In efforts to expand the SRC series, potential organizers are encouraged to contact SRC staff at Proposal guidelines can be found at

FASEB is composed of 30 societies with more than 125,000 members, making it the largest coalition of biomedical research associations in the United States. Our mission is to advance health and welfare by promoting progress and education in biological and biomedical sciences through service to our member societies and collaborative advocacy.

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