Public Release: 

Individual macromolecule motion in a crowded living cell

The research article embraces the status of the experimental situation and touches obstacles that still hinder the applications of single molecules in the cellular environment

Bentham Science Publishers

What's it about?

A universal theory on single molecules was drawn upon experimental facts by forming the concept of "The Meaningful Time Tm" acting as a fundamental natural law of single-molecule temporal resolution of freely diffusing molecules in dilute liquid and live cells (3D normal and anomalous diffusion) as well as in artificial or biological membranes (2D normal and anomalous diffusion). The single-molecule temporal resolution refers to the precision of a measurement with respect to the time of measuring just one and the same individual molecule. The physical law corresponds to the novel mathematical equations which we use to describe every single molecule.

It must be made clear that the underlying physics and molecular biochemistry can be modified easily but things hardly get worse when there is any trouble with the mathematics which rules the formulations. We prevailed and yet others did not.

Why is it important?

Because now it is possible to see macromolecules moving about in a living cell by super-resolution microscopy, we can study chemistry and biochemistry at a single-molecule level and in real life. And this is very important. Chemistry and biochemistry have traditionally been about studying a large number of molecules and the effect that they have.


Zeno Foldes-Papp
Visiting Professor of Medical Biochemistry
German University in Cairo, 2010 until present (Kudos scholarly reputation service, 2014 Thomson Reuters)

Present address:

Christian Clinical Center Siegen-Kreuztal
57223 Siegen-Kreuztal

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