New research suggests that a compound based on a spider toxin may be effective for treating pain.
Experiments conducted in rats revealed that the compound, called PnPP-19, provided pain relief most likely by acting on receptors in the nervous system that also bind opioids and cannabis (or marijuana). Interestingly, PnPP-19 is also being studied as a drug candidate to treat erectile dysfunction.
"Our findings reveal at least part of the mechanism of action underlying the pain relieving effects induced by PnPP-19," said Dr. Maria de Lima, lead author of the British Journal of Pharmacology study. "They also may contribute to the consideration of PnPP-19 as a potential lead compound for the development of new drug candidates to treat pain."
Wiley is a global provider of knowledge and knowledge-enabled services that improve outcomes in areas of research, professional practice and education. Through the Research segment, the Company provides digital and print scientific, technical, medical, and scholarly journals, reference works, books, database services, and advertising. The Professional Development segment provides digital and print books, online assessment and training services, and test prep and certification. In Education, Wiley provides education solutions including online program management services for higher education institutions and course management tools for instructors and students, as well as print and digital content. The Company's website can be accessed at http://www.