Public Release: 

NYU research: The struggle to maintain accurate data on the prevalence of opioid abuse

New York University

Nonmedical use of opioids (such as Vicodin, Percoset, and OxyContin) has become a major public health concern due to increases in treatment admissions, overdoses, and deaths. Data collected from high school seniors between 2009 and 2013 showed that 8.3% self-reported past-year nonmedical opioid use. Data have also shown a link from nonprescription opioid abuse to increased risk for heroin initiation and addiction, now widely considered one of the biggest public health challenges facing the U.S.

In a new study published in the American Journal of Drug and Alcohol Abuse by researchers at New York University's Center for Drug Use and HIV Research (CDUHR), lead researcher Joseph J. Palamar, PhD, MPH and his team sought to describe differences in self-reporting of nonmedical opioid use among high school seniors, who were asked about both general nonmedical opioid use and also specifically about nonmedical Vicodin and OxyContin use.

The data was drawn from the Monitoring the Future (MTF) survey, a nationwide ongoing annual study of the behaviors, attitudes, and values of American secondary school students. The MTF survey is administered in approximately 130 public and private schools throughout 48 states in the US. Roughly 15,000 high school seniors are assessed annually.

The results were not always clear-cut.

"If someone checks off that they haven't used opioids you'd expect them to check off 'no' to nonmedical use of Vicodin and OxyContin later in the survey, but this wasn't always the case," said Dr. Palamar, who is also an assistant professor of Population Health at the NYU Langone Medical Center (NYULMC). "A lot of these teens reported that they've never used opioids in a nonmedical manner, but later on they report nonmedical Vicodin and/or OxyContin use."

The survey defines opioids as painkillers such as Vicodin and OxyContin for those taking the survey, but Dr. Palamar explains that "it is likely that a lot of teens either don't read the definition of opioid or simply don't pay attention."

In order to determine the prevalence and correlates of discordant self-reports of nonmedical use of opioids, the researchers' analyses utilized the responses collected from 31,149 high school seniors (12th graders) between 2009 and 2013. The students were first asked how many times they had taken narcotics other than heroin without a doctor's instruction in the past year. Later in the survey students were asked the same question twice more, once with regard to Vicodin and a second time for OxyContin.

In total, 8.3% (2,585) said they had engaged in nonmedical opioid use, 7.6% (2,365) had engaged in nonmedical Vicodin use and 4.4% (1,381) reported nonmedical use of OxyContin. However, 37.1% of those reporting nonmedical Vicodin use and 28.2% of those reporting nonmedical OxyContin use did not report overall nonmedical opioid use earlier on.

"When combining responses, we found the 8.3% figure to be an underestimate" said Dr. Palamar. "When factoring in the discordant responses, we believe that 11.1% would more accurately represent prevalence of past-year nonmedical opioid use among the high school seniors."

The results underscore that medical and law enforcement communities may be underestimating opioid use and not just among younger populations.

"Accurate data on the prevalence of nonmedical opioid use is crucial to informing prevention and interventions, especially when considering that heroin initiation can be the next step in the addiction progression," said Dr. Palamar. "We need to do a better job of identifying the scope of the problem in order to correctly assign and deploy resources to combat the unprecedented rise in drug overdose deaths, which are now the leading cause of injury death in the U.S."

Surveys administered via pencil and paper, such as MTF, provide a unique opportunity to examine underreporting, as there is no mechanism for preventing contradictory responses, note the researchers. Electronically administered surveys can employ such mechanisms, however, the study's researchers are more concerned with drug education than survey design.

"Teens in the U.S. require a better drug education," said Dr. Palamar. "We recently found that teens have been underreporting ecstasy use because many don't know that Molly is ecstasy, and now we found that many teens aren't aware that Vicodin and OxyContin are categorized as opioids, narcotics, or painkillers."

The researchers feel that better drug education with honest information may be key to preventing future drug epidemics.

###

Researcher Affiliations:Joseph J. Palamara,b, Jenni A. Shearstona,c, and Charles M. Clelandb,d.

A. Department of Population Health, New York University Langone Medical Center, New York, NY, USA

B. Center for Drug Use and HIV Research, New York University College of Nursing, New York, NY, USA

C. College of Global Public Health, New York University, New York, NY, USA

D. College of Nursing, New York University, New York, NY, USA

Acknowledgements: The authors would like to thank the principal investigators of Monitoring the Future (PIs: Miech, Johnston, Bachman, O'Malley, and Schulenberg) at The University of Michigan, Institute for Social Research, Survey Research Center, and the Inter-university Consortium for Political and Social Research for providing access to these data (http://www.icpsr.umich.edu/icpsrweb/landing.jsp).

Funding: This work was supported by the National Institute of Drug Abuse at the National Institutes of Health (grant K01DA-038800 to JP, grant P30DA011041 to CC). Monitoring the Future data were collected through a research grant (R01DA-01411) from the National Institute on Drug Abuse.

About CDUHR

The mission of the Center for Drug Use and HIV Research (CDUHR) is to end the HIV and HCV epidemics in drug using populations and their communities by conducting transdisciplinary research and disseminating its findings to inform programmatic, policy, and grass roots initiatives at the local, state, national and global levels. CDUHR is a Core Center of Excellence funded by the National Institute on Drug Abuse (Grant #P30 DA011041). It is the first center for the socio-behavioral study of substance use and HIV in the United States and is located at the New York University College of Nursing. For more information, visit http://www.cduhr.org.

About NYU Langone Medical Center

NYU Langone Medical Center, a world-class, patient-centered, integrated academic medical center, is one of the nation's premier centers for excellence in clinical care, biomedical research, and medical education. Located in the heart of Manhattan, NYU Langone is composed of four hospitals--Tisch Hospital, its flagship acute care facility; Rusk Rehabilitation; the Hospital for Joint Diseases, the Medical Center's dedicated inpatient orthopaedic hospital; and Hassenfeld Children's Hospital, a comprehensive pediatric hospital supporting a full array of children's health services across the Medical Center--plus the NYU School of Medicine, which since 1841 has trained thousands of physicians and scientists who have helped to shape the course of medical history. The Medical Center's tri-fold mission to serve, teach, and discover is achieved 365 days a year through the seamless integration of a culture devoted to excellence in patient care, education, and research. For more information, go to http://www.NYULMC.org, and interact with us on Facebook, Twitter, and YouTube.

About the NYU Rory Meyers College of Nursing

NYU Rory Meyers College of Nursing is a global leader in nursing education, research, and practice. It offers a Bachelor of Science with a major in Nursing, a Master of Science and Post-Master's Certificate Programs, a Doctor of Nursing Practice degree and a Doctor of Philosophy in nursing research and theory development. http://nursing.nyu.edu/

About the NYU College of Global Public Health

At the College of Global Public Health (CGPH) at NYU, we are preparing the next generation of public health pioneers with the critical thinking skills, acumen and entrepreneurial approaches necessary to reinvent the public health paradigm. Devoted to employing a nontraditional, inter-disciplinary model, CGPH aims to improve health worldwide through a unique blend of global public health studies, research and practice. CGPH is located in the heart of New York City and extends to NYU's global network on six continents. Innovation is at the core of our ambitious approach, thinking and teaching. To learn more about CGPH, visit http://publichealth.nyu.edu/

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.