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High sea surface temperatures may affect immune competence of California sea lions

Pups born during warm years had lower antibody levels

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IMAGE: Sea surface temperature anomaly (°C) in the northeastern Pacific Ocean. view more 

Credit: Banuet-Martinez et al (2017)

Anomalously high sea surface temperatures may compromise the immune response of California sea lions, according to a study published June 28, 2017 in the open-access journal PLOS ONE by Karina Acevedo-Whitehouse from Autonomous University of Queretaro, Mexico, and colleagues.

During 2014 and 2015, sea surface temperatures on the Pacific Coast of North America were 2 to 5 ?C higher than normal. High sea surface temperatures decrease primary productivity and ultimately the availability of prey for marine mammals. California sea lions are likely to be particularly vulnerable to prey declines because they typically forage within 100 kilometers of their breeding sites. Prey declines could force them to extend foraging trips and eat lower value prey, which could affect pregnant and lactating females as well as pups.

Acevedo-Whitehouse and colleagues compared the body condition and immune competence of 61 California sea lion pups born on during 2014 and 2015, when sea surface temperatures were high, to those 23 pups born during 2013, when sea surface temperatures were normal. Data included blood levels of glucose, a marker of malnutrition, and IgG and IgA immunoglobulins, two different types of antibodies. In addition, the researchers tested pup responses to an immune challenge: injections of phytohemagglutinin, a plant-derived compound that stimulates division of immune system cells called T lymphocytes.

The researchers found that blood glucose was 15% lower in pups born when sea surface temperatures were high, suggesting that they were in early stages of starvation. These pups also had markedly lower levels of two immunoglobulins and were unable to respond to the immune challenge. This work suggests that atypical climatic conditions may limit energetic reserves and compromise the immune response in California sea lion pups, and could potentially leading to high death rates. Moreover, say the researchers, the entire northeastern Pacific ecosystem could likewise be vulnerable to high sea surface temperatures.

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In your coverage please use this URL to provide access to the freely available article in PLOS ONE: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0179359

Citation: Banuet-Martínez M, Espinosa-de Aquino W, Elorriaga-Verplancken FR, Flores-Morán A, García OP, Camacho M, et al. (2017) Climatic anomaly affects the immune competence of California sea lions. PLoS ONE 12(6): e0179359. https://doi.org/10.1371/journal.pone.0179359

Funding: This work was funded by a grant from the Autonomous University of Queretaro (Fund for the Advancement of Scientific Research, 142908; http://www.uaq.mx/dip/index.php/fofi-uaq) and partly funded by the Mexican Consejo Nacional de Ciencia y Tecnología (CONACYT; http://www.conacyt.gob.mx), grant numbers: CB-181876 and CB-153530. Data from the 2012 cohort was collected during a study funded by CONACYT grant number CB-153530. AFM, WEA and MBM are funded by CONACYT graduate scholarships 287579, 369084, and 778607, respectively. Publication fees were covered by support from the Programa de Fortalecimiento a la Calidad Educativa, PFCE 2016 (Mexico). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

Competing Interests: The authors have declared that no competing interests exist.

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