Public Release: 

Brain lays foundation for reason in childhood

Society for Neuroscience

Structural connections between frontal and parietal areas in children's brains can predict their ability to reason later in life, reports new research published in The Journal of Neuroscience.

Carter Wendelken, Silvia Bunge and colleagues previously found that coordinated activity of the rostrolateral prefrontal cortex (RLPFC) and inferior parietal lobe (IPL) is associated with the ability to solve novel problems in adolescents 12 years of age and older. However, it remained unclear whether this functional connectivity is preceded by or drives the development of white matter connections (structural connectivity) and how these changes related to reasoning ability.

Analyzing longitudinal data from multiple studies of children ages 6 to 22, the researchers found that strong structural connectivity between RLPFC and IPL in younger children is associated with both increased functional connectivity and improved reasoning in adolescence and adulthood. The results suggest that the anatomical connection between these regions develops during the early school years and enables coordinated brain activity that supports an important cognitive function later in life.


Article: Fronto-parietal structural connectivity in childhood predicts development of functional connectivity and reasoning ability: a large-scale longitudinal investigation


Corresponding authors: Carter Wendelken, and Silvia Bunge, (University of California at Berkeley, Berkeley, CA, USA)

About JNeurosci

The Journal of Neuroscience (JNeurosci) is the flagship journal of the Society for Neuroscience. JNeurosci publishes papers on a broad range of topics in neuroscience in a print edition each Wednesday and recently began publishing early-release PDFs of studies online shortly after acceptance. The Society for Neuroscience is the world's largest organization of scientists and physicians devoted to understanding the brain and nervous system. The nonprofit organization, founded in 1969, now has nearly 37,000 members in more than 90 countries and over 130 chapters worldwide.

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