Using infrared spectroscopy and chemometric techniques to analyze blood plasma samples from a cohort of 347 participants with neurodegenerative diseases and 202 healthy controls, 23-90 years of age, researchers identified cases of Alzheimer's disease (AD) with up to 86% sensitivity and specificity, and early AD cases with 80% sensitivity and 74% specificity; additionally, the researchers differentiated AD from dementia with Lewy bodies with 90% sensitivity and specificity, findings with potential implications for developing noninvasive methods for diagnosing neurodegenerative diseases.
Article #17-01517: "Differential diagnosis of Alzheimer's disease using spectrochemical analysis of blood," by Maria Paraskevaidi et al.
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