Human populations have always been exposed to ionizing radiation, and more so in modern life due to its use in medicine, industry and the armed forces. Whilst the risks to human health from medium and high-level radiation are relatively well-understood, the risks at lower levels are less clear. Mixed messages about the safety of low doses of radiation from different sources have created confusion for the public and for policy makers.
In a new study, published today in the Proceedings of the Royal Society, a team of experts from the Oxford Martin School at the University of Oxford have compiled the evidence on health risks from low-level ionizing radiation, adding a new nuance to the debate. The restatement is intended to better inform policy decisions and show where crucial gaps in knowledge lie. It clarifies the scientific evidence available from a variety of sources, and ranks them as to how much they enjoy consensus support from the scientific community. The paper concludes that the overall risk to human health from low-level radiation exposure is small, particularly when compared with general risks from modern society, such as obesity, smoking and air pollution.
Professor Angela McLean, lead author and Co-Director at the Oxford Martin Programme on Collective Responsibility for Infectious Disease, said: 'We know a great deal about the health risks from radiation thanks to exceptionally careful studies of groups of people exposed to different levels from nuclear bombs or accidents, medical exposure of patients, naturally occurring sources (such as radon), and workers in the nuclear industry and medicine. From these studies it is clear that moderate and high doses of radiation increase the risk of developing some types of cancer.'
The team illustrate the size of this increase in risk by using the following example. 100 individuals were each briefly exposed to 100 mSv (millisievert is the measure of radiation dose), then, on average over a lifetime, one of them would be expected to develop a radiation-induced cancer, whereas 42 of them would be expected to develop cancer from other causes. To put 100 mSv in context, the low dose from a CT scan of the whole spine is 10 mSv, while the average dose from natural background radiation in the UK is 2.3 mSv each year.
To build on the insights gained from this study, further research will be conducted to better understand the genetic healthcare implications of radiation exposure and the biological basis of the damage from radiation to DNA and cells.
Professor McLean said; 'Despite the depth of our knowledge, there are still many unknowns. Even the best designed epidemiological study finds it hard to distinguish between no extra risk and a small additional risk at low levels of exposure and we have to make some important assumptions here, particularly for the purposes of radiation protection. For example, no human study has conclusively shown an increase in hereditary disease in the children of irradiated parents, but radiation protection calculations assume some risk is present because of evidence from large animal experiments.
'There is also a great deal of work being undertaken to investigate the biological basis of the damage from radiation to DNA and cells, but it is still not clear precisely the steps by which a dose of radiation might lead to cancer, sometimes decades later'.
NOTES TO EDITORS:
The full paper, "A restatement of the natural science evidence base concerning the health effects of low-level ionizing radiation" can be downloaded at http://www.
Professor Angela Mclean is All Souls Senior Research Fellow in Theoretical Life Sciences and Professor of Mathematical Biology at Oxford University. She is also Co-Director at the Oxford Martin Programme on Collective Responsibility for Infectious Disease.
Oxford Martin Restatements
Oxford Martin Restatements review the natural science evidence base underlying areas of current policy concern and controversy. Written in policy neutral terms and designed to be read by an informed but not technically specialist audience, restatements are produced by a writing team reflecting the breadth of opinion on the topic in the science community and involve wide consultation with interested stakeholders. The final version of the restatement is peer-reviewed prior to publication.
The Oxford Martin School
The Oxford Martin School at the University of Oxford is a world-leading centre of pioneering research that addresses global challenges. It invests in research that cuts across disciplines to tackle a wide range of issues such as climate change, disease and inequality. The School supports novel, high risk and multidisciplinary projects that may not fit within conventional funding channels, because breaking boundaries can produce results that could dramatically improve the wellbeing of this and future generations. Underpinning all our research is the need to translate academic excellence into impact - from innovations in science, medicine and technology, through to providing expert advice and policy recommendations.
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