News Release

First time mums with an epidural who lie down more likely to have a normal birth

Peer-Reviewed Publication

University of Birmingham

Adopting a lying down position rather than being upright in the later stages of labour for first-time mothers who have had a low dose epidural leads to a higher chance of them delivering their baby without any medical intervention, a study has found.

Professors Peter Brocklehurst and Christine McArthur, as well as statistics lead Pollyanna Hardy, of the University of Birmingham, and their colleagues within the Epidural and Position Trial Collaborative Group were behind the randomised controlled trial involving 3,093 women who gave birth across 41 UK hospitals between October 2010 and January 2014.

The aim of the BUMPES trial, funded by the National Institute for Health Research, was to investigate whether adopting an upright position in the second stage of labour in first-time mothers who have a low-dose epidural would lead to an increase in the number who had a spontaneous vaginal birth - without the need for forceps or suction.

The results of the study, in which women were randomly allocated an upright or lying down position (lying on the left or right side) during the later stages of labour were published today in The BMJ.

The study found that there were fewer spontaneous vaginal births in women in the upright group (35.2%), compared with women in the lying down group (41.1%). This represents a 5.9% absolute increase in the chance of spontaneous birth in the lying down group.

In the UK, around 30% of women choose to have an epidural as it's the most effective form of pain relief in labour. However, having an epidural leads to an increased risk of an instrumental vaginal birth (forceps or vacuum).

The position a woman is in during the second stage of labour (after the cervix is fully dilated) has been suggested to have an effect on the risk of an instrumental vaginal birth and current existing guidance in the UK recommends that women with an epidural should be encouraged to adopt an upright position.

Professor Peter Brocklehurst, of the Institute of Applied Health Research at the University of Birmingham, said: "The study provides evidence that first time mothers with an epidural who lie down on their side during the second stage of labour are more likely to have a spontaneous vaginal birth, with no apparent disadvantages in relation to short or longer term outcomes for mother or baby.

"Like all clinical trials, the study does have its limitations and we can only speculate about the mechanism by which a lying down position increases the chance of a spontaneous vaginal birth.

"However, the evidence we have found from this large trial group provides an easy and cost-free intervention in our labour wards. Pregnant women, in consultation with their healthcare providers, can now make informed choices about their position in the second stage of labour.

"The results from this trial apply only to first-time mothers in the second stage of labour with low dose epidural analgesia. Therefore it is unclear what the findings may mean for women who have given birth before and are in labour with an epidural. However, given the clear benefit of the lying down position, perhaps all women who have an epidural should be offered the choice of adopting a lying down position in the second stage until we know otherwise."

He said that the results of the BUMPES trial strongly support the need for a similar large trial to find the best position for women in the second stage of labour who do not have an epidural.

###

For more information contact Emma McKinney, Communications Manager (Health Science), University of Birmingham, on 0121 414 6681 or email e.j.mckinney@bham.ac.uk

Notes to Editors:

* The University of Birmingham is ranked amongst the world's top 100 institutions. Its work brings people from across the world to Birmingham, including researchers, teachers and more than 5,000 international students from over 150 countries.

* The Epidural and Position Trial Collaborative Group (2017). 'Upright versus lying down position in second stage of labour in nulliparous women with low dose epidural: BUMPES randomised controlled trial'. The BMJ.

* The Epidural and Position Trial Collaborative Group consists of Debra Bick, Kings College London, Professor of Evidence Based Midwifery Practice, Annette Briley, Guys and St Thomas's NHS Foundation Trust, Consultant Midwife, Peter Brocklehurst, University of Birmingham, Professor of Women's Health and UCL, Professor of Women's Health, Pollyanna Hardy, Senior Trials Statistician formerly at University of Oxford and now at University of Birmingham, Edmund Juszczak, University of Oxford, Associate Professor of Clinical Trials, Lynn Lynch, Cardiff University, Midwifery Lecturer, Christine MacArthur, University of Birmingham, Professor of Maternal and Child Epidemiology, Phillip Moore, University Hospital Birmingham NHS Trust, Consultant Anaesthetist, Mary Nolan, University of Worcester, Professor of Perinatal Education, Oliver Rivero-Arias, University of Oxford, Senior Health Economist, Julia Sanders, Cardiff & Vale Health Board, Consultant Midwife and Cardiff University, Reader in Midwifery, Andrew Shennan, Kings College London, Professor of Obstetrics, Matt Wilson, Sheffield Teaching Hospital, Consultant in Obstetric Anaesthesia and University of Sheffield, Senior Lecturer in Anaesthesia.

* This report presents independent research commissioned by the National Institute for Health Research (NIHR). The views and opinions expressed by authors in this publication are those of the authors and do not necessarily reflect those of the NHS, the NIHR, MRC, CCF, NETSCC, the HTA programme or the Department of Health.


Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.