Public Release: 

Many women do not follow contraception guidelines after weight-loss surgery, Pitt study finds

University of Pittsburgh Schools of the Health Sciences

PITTSBURGH, Oct. 17, 2017 - Many women do not follow the guidelines to prevent pregnancy for an 18-month period following bariatric surgery, University of Pittsburgh researchers examining post-surgery contraceptive practices and conception rates report.

The study results are published online and will be featured in the November print issue of the American College of Obstetricians and Gynecologists Obstetrics & Gynecology journal.

The American Society for Metabolic & Bariatric Surgery recommends that women avoid conception for the first year-and-a-half following weight-loss surgery to optimize the likelihood of maternal weight stability during fetal growth. Despite the recommendation, four percent of study participants were actively trying to get pregnant and an additional 42 percent reported having unprotected intercourse during this at-risk post-surgical timeframe.

"This is concerning given recent research suggests that bariatric surgery increases the risk for small-for-gestational-age newborns, preterm deliveries and neonatal intensive care unit admissions in the first 18 months after surgery," said lead author Marie Menke, M.D., assistant professor of obstetrics, gynecology and reproductive sciences at Pitt's School of Medicine and Magee-Womens Hospital of UPMC. "Our findings highlight a public health issue that merits additional scrutiny regarding contraceptive counseling before and after surgery, and provision of contraceptive services for all reproductive-aged women undergoing bariatric surgery."

The study used data collected through the NIH-funded Longitudinal Assessment of Bariatric Surgery (LABS) consortium, which has its data coordinating center at Pitt's Graduate School of Public Health, and includes 10 hospitals throughout the U.S., including a large clinical center at Magee-Womens Hospital of UPMC.

Menke and colleagues analyzed data from 710 women ages 18 to 44 with no use of hormone replacement therapy and no history of menopause or hysterectomy. In addition to a preoperative assessment, study participants answered a yearly post-operative reproductive questionnaire, which included questions about past-year attempts to conceive, contraceptive use and pregnancies. Study participants filled out an additional assessment after each pregnancy.

"Contraceptive counseling both before and after bariatric surgery are critical pieces of the multidisciplinary needs of the bariatric patient. This study clearly shows that early conception rates and contraceptive practices after bariatric surgery are not ideal," said study co-author Anita Courcoulas, M.D., M.P.H., F.A.C.S., director, minimally invasive bariatric and general surgery at Magee-Womens Hospital of UPMC. "The findings highlight the need for more frequent referral to counseling for contraception guidance throughout the bariatric surgery process."

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Additional authors on this study are Wendy C. King, Ph.D., and Gretchen E. White, M.P.H., both of Pitt Public Health; Gabriella G. Gosman, M.D., of UPMC; Gregory F. Dakin, M.D., and Alfons Pomp, M.D., both of Weill Cornell Medical College; David R. Flum, M.D., M.P.H., of the University of Washington; Molly J. Orcutt, D.O., and Kristine J. Steffen, Ph.D., Pharm.D., both of the Neuropsychiatric Research Institute and North Dakota State University; Walter J. Pories, M.D., of East Carolina University; Jonathan Q. Purnell, M.D., and Bruce M. Wolfe, M.D., of the Oregon Health Sciences University; and Susan Z. Yanovski, M.D., of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).

This clinical study was a cooperative agreement funded by the NIDDK. Grant numbers: Data Coordinating Center - U01 DK066557; Columbia - U01-DK66667 (in collaboration with Cornell University Medical Center CTSC, grant UL1-RR024996); University of Washington - U01-DK66568 (in collaboration with CTRC, grant M01RR-00037); Neuropsychiatric Research Institute - U01-DK66471; East Carolina University - U01-DK66526; UPMC - U01-DK66585 (in collaboration with CTRC, grant UL1-RR024153); and Oregon Health & Science University - U01-DK66555. Menke was funded by the NICHD (K12 HD 063087).

About the University of Pittsburgh Graduate School of Public Health

The University of Pittsburgh Graduate School of Public Health, founded in 1948 and now one of the top-ranked schools of public health in the United States, conducts research on public health and medical care that improves the lives of millions of people around the world. Pitt Public Health is a leader in devising new methods to prevent and treat cardiovascular diseases, HIV/AIDS, cancer and other important public health problems. For more information about Pitt Public Health, visit the school's Web site at http://www.publichealth.pitt.edu.

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