Public Release: 

What's new in the field of microbiota and bone health?

Eight outstanding reviews in Calcified Tissue International give valuable insight into exciting new research on the gut-musculoskeletal axis

International Osteoporosis Foundation

The human microbiota is made up of trillions of cells which include bacteria, viruses and fungi, with the largest populations of human microbiota residing in the gut.

A large body of research has begun to detail the mechanism(s) of how microbiota interact with the host to maintain optimal health status, including in regard to musculoskeletal health. It is an exciting and very complex field, as gut microbiota can vary according to age, diet, sex, living conditions, and diseases requiring antibiotic- and drug treatment.

In a special issue of Calcified Tissue International, eight invited reviews authored by renowned experts in the field provide a comprehensive overview of the latest knowledge and research developments related to the gut-musculoskeletal axis:

Editorial: Microbiota and Bone Health: The Gut-Musculoskeletal Axis
Rizzoli, R. Calcif Tissue Int (2018)

Advances in Probiotic Regulation and Mineral Metabolism
McCabe, L.R. & Parameswaran, N. Calcif Tissue Int (2018)

Gut Microbiota and IGF-1
Yan, J. & Charles, J.F. Calcif Tissue Int (2018)

Gut Microbiota and Host Juvenile Growth
Schwarzer, M., Strigini, M. & Leulier, F. Calcif Tissue Int (2017)

Gut Microbiota, Immune System, and Bone
D'Amelio, P. & Sassi, F. Calcif Tissue Int (2017)

Osteomicrobiology: A New Cross-Disciplinary Research Field
Ohlsson, C. & Sjögren, K. Calcif Tissue Int (2017)

Gut Microbiota Contribute to Age-Related Changes in Skeletal Muscle Size, Composition, and Function: Biological Basis for a Gut-Muscle Axis
Grosicki, G.J., Fielding, R.A. & Lustgarten, M.S. Calcif Tissue Int (2017).

Prebiotics, Bone and Mineral Metabolism
Whisner, C.M. & Castillo, L.F. Calcif Tissue Int (2017)

Rizzoli R, Biver E (2018) Effects of Fermented Milk Products on Bone
Rizzoli, R. & Biver, E. Calcif Tissue Int (2017)


About Calcified Tissue International & Musculoskeletal Research

Calcified Tissue International & Musculoskeletal Research is a peer-reviewed journal which publishes original preclinical, translational and clinical research, and reviews concerning the structure and function of bone, and other musculoskeletal tissues in living organisms, as well as clinical studies of musculoskeletal disease. It includes studies of cell biology, molecular biology, intracellular signalling, and physiology, as well as research into the hormones, cytokines and other mediators that influence the musculoskeletal system. The journal also publishes clinical studies of relevance to bone disease, mineral metabolism, muscle function, and musculoskeletal interactions. 2016 Impact Factor: 3.125

Editors in Chief: Stuart Ralston and René Rizzoli; Musculoskeletal Research Section Editor: Roger Fielding

About IOF

The International Osteoporosis Foundation (IOF) is the world's largest nongovernmental organization dedicated to the prevention, diagnosis and treatment of osteoporosis and related musculoskeletal diseases. IOF members, including committees of scientific researchers as well as 240 patient, medical and research societies in 99 locations, work together to make fracture prevention and healthy mobility a worldwide heath care priority. / @iofbonehealth

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.