Amsterdam, August 27, 2018 - Over the past 50 years researchers, clinicians, professional organizations, and health charities have waged war on sugar, calling for dietary recommendations to be changed and for a sugar tax on soft drinks and sweet treats in an effort to reduce obesity and cardiovascular diseases. In 2014, the WHO recommended that adults and children reduce their daily intake of free sugars to less than ten percent of their total energy intake. But could the war on sugar be bad for your health? Experts present the arguments both for and against sugar in this hotly contested debate on the "Sugar Wars" published in Progress in Cardiovascular Diseases.
In his article, Edward Archer, PhD, of EvolvingFX, Jupiter, FL, USA, challenged the latest dietary recommendations and presented evidence from multiple domains to show that "diet" is a necessary but trivial factor in metabolic health. "Anti-sugar rhetoric is simply diet-centric disease-mongering engendered by physiologic illiteracy," he wrote. "My position is that dietary sugars are not responsible for obesity or metabolic diseases and that the consumption of simple sugars and sugar-polymers (e.g., starches) up to 75 percent of total daily caloric intake is innocuous in healthy individuals."
In defense of sugar, Dr. Archer argues that:
- Biological life depends on sugar in its many forms, for example, sugars and sugar-polymers are major nutritive constituents of many foods and beverages including breast milk, dairy products, fruit, fruit juices, honey, sucrose (i.e., table sugar; a disaccharide of glucose, and fructose), sugar-sweetened beverages, rice, beans, potatoes, wheat, corn, quinoa, and other cereal grains.
- Sugars and sugar-polymers have played critical roles in both human evolution and dietary history and were the major sources of nutrient-energy (calories) for most of the global population throughout human history.
- "Diet-centric" researchers often ignore the fact that physical activity, not diet, is the major modifiable determinant of metabolic health.
- The consumption of dietary sugars up to 80 percent of total energy intake is entirely innocuous in active populations.
- There is strong, positive association between sugar availability/consumption and health.
- Obesity and type 2 diabetes mellitus are not diet-related diseases but are metabolic conditions caused by the positive energy balance (i.e., over-nutrition) driven by physical inactivity in past and current generations.
In a Letter to the Editor, James J. DiNicolantonio, PharmD, and James H. O'Keefe, MD, of the Department of Preventive Cardiology, Saint Luke's Mid America Heart Institute, Kansas City, MI, USA, provide strong criticisms to Dr. Archer's positions by arguing that dietary sugar (either glucose, sucrose, or high-fructose corn syrup) is not necessary for life, and that humans did not consume refined sucrose or high fructose corn syrup throughout most of their evolution.
"The truth is you really can't outrun a bad diet, especially when it comes to overconsuming refined sugar. While it's true that exercise may reduce the risk of obesity from overconsuming refined sugar, it doesn't prevent dental cavities, inflammation of the gums, or inflammation that occurs in the intestine, liver, and kidneys when the body processes large amounts of sugar," say Dr. DiNicolantonio and Dr. O'Keefe. "Healthy populations that consume fairly high amounts of raw honey who also live hunter-gatherer lifestyles should not be used as an example to give an industrialized sedentary population an excuse to overconsume refined sugar. Importantly, raw honey is not the same as refined sugar."
In his rebuttal, Dr. Archer reasserts that obesity and metabolic diseases are caused by the confluence of physical inactivity and non-genetic evolutionary processes over many generations. He points out that by the late 1940s, both the life- and health-spans in the USA had increased dramatically despite half of all infants being reared on infant formula - a 100 percent artificial/synthetic product containing around 40 percent of calories from added sugars (e.g., lactose, sucrose, glucose, fructose, and/or corn syrup). He concludes: "It is time for the medical and scientific communities to return to their roots, eschew magical and miraculous thinking, and demonstrate a modicum of skepticism by refuting the illiterate nonsense and puritanical proscriptions engendered by diet-centrism."
In an accompanying Editorial, Carl J. "Chip" Lavie, MD, FACC, FACP, FCCP, of the Ochsner Clinical School, The University of Queensland School of Medicine, New Orleans, LA, USA, and Editor of Progress in Cardiovascular Diseases, states his personal belief that the ill effects of sugar have been over-emphasized by scientists and, especially, by the media. "Most sedentary people who are gaining weight and/or have high glucose and/or triglycerides should limit their carbohydrates and, especially, simple sugars, but for lean physically active individuals without these characteristics, sugars and carbohydrates are not toxic and, in fact, are probably helpful." Dr. Lavie, however, feels it is important to have the scientists discuss opposing viewpoints in the journal.
Notes for editors
The articles published in Progress in Cardiovascular Diseases are:
"In Defense of Sugar: A Critique of Diet-Centrism," by Edward Archer (https:/
Author contact: Edward Archer at email@example.com
"Sugar Wars-Commentary From the Editor," by Carl J. Lavie, (https:/
Author contact: Carl J. "Chip" Lavie at firstname.lastname@example.org
"Letter to the Editor - In Critique of 'In Defense of Sugar': The Nuance of Whole Foods," by James J. DiNicolantonio and James H. O'Keefe (https:/
Author contact: James J. DiNicolantonio at email@example.com
"Response to the Letter to the Editor by author of review - The Demonization of 'Diet' Is Nothing New," by Edward Archer (https:/
Full text of the articles is available to journalists upon request. To obtain copies contact Jonathan Davis, Communications Officer, Elsevier, at +31 20 485 2719 or firstname.lastname@example.org. Journalists wishing to set up interviews with the authors should also contact Jonathan Davis.
About Progress in Cardiovascular Diseases
Each issue of Progress in Cardiovascular Diseases comprehensively covers a single topic in the understanding and treatment of disorders of the heart and circulation. Some issues include special articles, definitive reviews that capture the state of the art in the management of clinical problems in cardiology. http://www.
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