Researchers in Columbia, South America, conducted a retrospective observational study within six hospitals to identify risk factors of maternal mortality in mechanically ventilated pregnant patients.
The study included 2,116 obstetric patients, with the median age of 26, who were admitted to the ICU and who required mechanical ventilation for more than 24 hours between. Survivors and nonsurvivors were compared using univariate statistics and logistic regression. In addition, a discrimination analysis was conducted continuously on clinical and laboratory variables, to best evaluate their ability to predict mortality.
Of the 2,116 patients, 299 (14 percent) pregnant women within the study had acute respiratory failure and required mechanical ventilation. Obstetric hemorrhage, hypertensive disorders of pregnancy and maternal sepsis were the most common indications for mechanical ventilation. Factors related to higher mortality included the use a vasopressor, blood transfusions, neurological dysfunction, coagulopathy and ARDS.
"The mortality related to mechanical ventilation in obstetric patients has the same associated factors as in the non-obstetric population," says Dr. Jose A. Rojas-Suarez, lead researcher. "The results show that ARDS, the presence of coagulopathy and neurological dysfunction are clinical factors associated with mortality."
Further results from these two studies will be shared at CHEST Annual Meeting 2018 in San Antonio on Monday, Oct. 8, 7:45 a.m. to 8:00 a.m., at the Henry B. Gonzalez Convention Centre, Room 206A. The study abstracts can be viewed on the journal CHEST® website.
ABOUT CHEST 2018
CHEST 2018 is the 84th annual meeting for the American College of Chest Physicians held Oct. 6 to Oct. 10, 2018, in San Antonio, Texas. The American College of Chest Physicians, publisher of the journal CHEST®, is the global leader in advancing best patient outcomes through innovative chest medicine education, clinical research and team-based care. Its mission is to champion the prevention, diagnosis and treatment of chest diseases through education, communication and research. It serves as an essential connection to clinical knowledge and resources for its 19,000 members from around the world who provide patient care in pulmonary, critical care and sleep medicine. For more information about CHEST 2018, visit chestmeeting.chestnet.org, or follow CHEST meeting hashtag, #CHEST2018, on social media.